Acute Lymphoblastic Leukaemia Group

Research output

Research output per year 1997 2019 2020 2021 2022 2023 2024

• 67 Article
• 8 Letter
• 7 Review article
• 2 Editorial
• 1 More
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2024

  Asciminib is a novel inhibitor of ABL1 and ABL2 gene fusions in ALL but requires the ABL SH3 domain for efficacy

  Eadie, L. N., Lagonik, E., Page, E. C., Schutz, C. E., Heatley, S. L., McClure, B. J., Forgione, M. O., Yeung, D. T., Hughes, T. P. & White, D. L., 2024, (Accepted/In press) In: Blood.

  Research output: Contribution to journal › Article › peer-review

• Clinical outcomes of chronic myeloid leukaemia patients taking asciminib through a Managed Access Programme (MAP) in Australia

  Chee, L., Lee, N., Grigg, A., Chen, M., Schwarer, A., Szer, J., Ratnasingam, S., Raj, S., Lukito, P., Yeung, D., Hughes, T. & Shanmuganathan, N., 2024, (Accepted/In press) In: Internal Medicine Journal.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• How comparable are patient outcomes in the “real-world” with populations studied in pivotal AML trials?

  Tiong, I. S., Wall, M., Bajel, A., Kalro, A., Fleming, S., Roberts, A. W., Thiagarajah, N., Chua, C. C., Latimer, M., Yeung, D., Marlton, P., Johnston, A., Enjeti, A., Fong, C. Y., Cull, G., Larsen, S., Kennedy, G., Schwarer, A., Kipp, D. & Ramanathan, S. & 18 others, Verner, E., Tiley, C., Morris, E., Hahn, U., Moore, J., Taper, J., Purtill, D., Warburton, P., Stevenson, W., Murphy, N., Tan, P., Beligaswatte, A., Mutsando, H., Hertzberg, M., Shortt, J., Szabo, F., Dunne, K. & Wei, A. H., Dec 2024, In: Blood Cancer Journal. 14, 1, 54.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Laboratory validation and clinical utility of next-generation sequencing-based IGH/TCR clonality testing for the monitoring of measurable residual disease in acute lymphoblastic leukaemia: real-world experience at Austin Pathology

  Ma, S. B., Lin, W., Campbell, J., Clerici, K., White, D., Yeung, D., Gorniak, M., Fleming, S., Fong, C. Y. & Agarwal, R., 2024, (Accepted/In press) In: Pathology.

  Research output: Contribution to journal › Article › peer-review

• Population pharmacokinetics of posaconazole in allogeneic haematopoietic stem cell transplant patients

  Selby, P. R., Heffernan, A. J., Yeung, D., Warner, M. S., Peake, S. L., Hahn, U., Westley, I., Shakib, S. & Roberts, J. A., 1 Mar 2024, In: Journal of Antimicrobial Chemotherapy. 79, 3, p. 567-577 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)
• 2023

  Adverse outcomes for chronic myeloid leukemia patients with splenomegaly and low in vivo kinase inhibition on imatinib

  Kok, C. H., Saunders, V. A., Dang, P., Shanmuganathan, N., White, D., Branford, S., Yeung, D. & Hughes, T. P., Dec 2023, In: Blood Cancer Journal. 13, 1, 143.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• ANZTCT consensus position statement on ruxolitinib in steroid-refractory acute and chronic graft-versus-host disease

  Hamad, N., Bilmon, I., Chee, L., Henden, A., Johnston, A., Purtill, D., Bajel, A., Tey, S. K., Yeung, D., Cole, T., Lewis, C. & Butler, J., 28 Nov 2023, (E-pub ahead of print) In: Internal Medicine Journal. 53, 12, p. 2319-2329 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A Personalized Risk Model for Azacitidine Outcome in Myelodysplastic Syndrome and Other Myeloid Neoplasms Identified by Machine Learning Model Utilizing Real-World Data

  Sharplin, K., Proudman, W., Chhetri, R., Tran, E. N. H., Choong, J., Kutyna, M., Selby, P., Sapio, A., Friel, O., Khanna, S., Singhal, D., Damin, M., Ross, D., Yeung, D., Thomas, D., Kok, C. H. & Hiwase, D., Aug 2023, In: Cancers. 15, 16, 4019.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Case report: Rare case of donor cell-derived T-cell acute lymphoblastic leukaemia in a female patient after receiving an allo-transplant from her male sibling

  Eadie, L. N., Rehn, J. A., Schutz, C. E., Heatley, S. L., Kutyna, M. M., Hiwase, D. K., White, D. L. & Yeung, D. T., Oct 2023, In: British Journal of Haematology. 203, 2, p. 282-287 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Case Report: Rare IKZF1 Gene Fusions Identified in Neonate with Congenital KMT2A-Rearranged Acute Lymphoblastic Leukemia

  Eadie, L. N., Rehn, J. A., Breen, J., Osborn, M. P., Jessop, S., Downes, C. E. J., Heatley, S. L., McClure, B. J., Yeung, D. T., Revesz, T., Saxon, B. & White, D. L., Feb 2023, In: Genes. 14, 2, 264.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Factors predicting survival following alloSCT in patients with therapy-related AML and MDS: a multicenter study

  Baranwal, A., Chhetri, R., Yeung, D., Clark, M., Shah, S., Litzow, M. R., Hogan, W. J., Mangaonkar, A., Alkhateeb, H. B., Singhal, D., Cibich, A., Bardy, P., Kok, C. H., Hiwase, D. K. & Shah, M. V., Jul 2023, In: Bone Marrow Transplantation. 58, 7, p. 769-776 8 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Gain of chromosome 21 increases the propensity for P2RY8: :CRLF2 acute lymphoblastic leukemia via increased HMGN1 expression

  Page, E. C., Heatley, S. L., Rehn, J., Thomas, P. Q., Yeung, D. T. & White, D. L., 2023, In: Frontiers in Oncology. 13, 1177871.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• Immune modulation in chronic myeloid leukaemia patients treated with nilotinib and interferon-alpha

  Irani, Y. D., Hughes, A., Kok, C. H., Clarson, J., Yeung, D. T., Ross, D. M., Branford, S., Hughes, T. P. & Yong, A. S. M., Sept 2023, In: British Journal of Haematology. 202, 6, p. 1127-1136 10 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Lineage-specific detection of residual disease predicts relapse in patients with chronic myeloid leukemia stopping therapy

  Pagani, I. S., Shanmuganathan, N., Dang, P., Saunders, V. A., Grose, R., Kok, C. H., James, J., Tolland, M., Braley, J. A., Altamura, H. K., Yeung, D. T., Branford, S., Yong, A. S. M., Hughes, T. P. & Ross, D. M., 24 Aug 2023, (E-pub ahead of print) In: Blood. 142, 25, p. 2192-2197 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Paediatric B lymphoblastic leukaemia with hyperdiploidy and a false-positive KMT2A fluorescence in situ hybridization result

  Nunn, J., Adayapalam, N., Riyat, S., Seymour, L., Williams, B., Rehn, J., White, D., Moore, A. S. & Tsuchiya, K., Nov 2023, In: Cancer Genetics. 278-279, p. 80-83 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Population Pharmacokinetics of Ganciclovir in Allogeneic Hematopoietic Stem Cell Transplant Patients

  Selby, P. R., Heffernan, A. J., Yeung, D., Warner, M. S., Peake, S. L., Hahn, U., Wallis, S. C., McWhinney, B., Ungerer, J. P. J., Shakib, S. & Roberts, J. A., Mar 2023, In: Antimicrobial Agents and Chemotherapy. 67, 3

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• Reproducible Bioinformatics Analysis Workflows for Detecting IGH Gene Fusions in B-Cell Acute Lymphoblastic Leukaemia Patients

  Thomson, A. J., Rehn, J. A., Heatley, S. L., Eadie, L. N., Page, E. C., Schutz, C., McClure, B. J., Sutton, R., Dalla-Pozza, L., Moore, A. S., Greenwood, M., Kotecha, R. S., Fong, C. Y., Yong, A. S. M., Yeung, D. T., Breen, J. & White, D. L., Oct 2023, In: Cancers. 15, 19, 4731.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• The acquisition order of leukemic drug resistance mutations is directed by the selective fitness associated with each resistance mechanism

  Leow, B. C. S., Kok, C. H., Yeung, D. T., Hughes, T. P., White, D. L. & Eadie, L. N., Dec 2023, In: Scientific reports. 13, 1, 13110.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype

  Hiwase, D., Hahn, C., Tran, E. N. H., Chhetri, R., Baranwal, A., Al-Kali, A., Sharplin, K., Ladon, D., Hollins, R., Greipp, P., Kutyna, M., Alkhateeb, H., Badar, T., Wang, P., Ross, D. M., Singhal, D., Shanmuganathan, N., Bardy, P., Beligaswatte, A. & Yeung, D. & 21 others, Litzow, M. R., Mangaonkar, A., Giri, P., Lee, C., Yong, A., Horvath, N., Singhal, N., Gowda, R., Hogan, W., Gangat, N., Patnaik, M., Begna, K., Tiong, I. S., Wei, A., Kumar, S., Brown, A., Scott, H., Thomas, D., Kok, C. H., Tefferi, A. & Shah, M. V., 2 Mar 2023, In: Blood. 141, 9, p. 1087-1091 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Citations (Scopus)
• 2022

  Case Report: Precision Medicine Target Revealed by In Vitro Modeling of Relapsed, Refractory Acute Lymphoblastic Leukemia From a Child With Neurofibromatosis

  Heatley, S. L., Page, E. C., Eadie, L. N., McClure, B. J., Rehn, J., Yeung, D. T., Osborn, M., Revesz, T., Kirby, M. & White, D. L., 20 Apr 2022, In: Frontiers in Oncology. 12, 851572.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemia

  Kimura, S., Montefiori, L., Iacobucci, I., Zhao, Y., Gao, Q., Paietta, E. M., Haferlach, C., Laird, A. D., Mead, P. E., Gu, Z., Stock, W., Litzow, M., Rowe, J. M., Luger, S. M., Hunger, S. P., Ryland, G. L., Schmidt, B., Ekert, P. G., Oshlack, A. & Grimmond, S. M. & 16 others, Rehn, J., Breen, J., Yeung, D., White, D. L., Aldoss, I., Jabbour, E. J., Pui, C. H., Meggendorfer, M., Walter, W., Kern, W., Haferlach, T., Brady, S., Zhang, J., Roberts, K. G., Blombery, P. & Mullighan, C. G., 16 Jun 2022, In: Blood. 139, 24, p. 3519-3531 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Citations (Scopus)

• Exploring the oncogenic and therapeutic target potential of the MYB-TYK2 fusion gene in B-cell acute lymphoblastic leukemia

  Shirazi, P. T., Eadie, L. N., Heatley, S. L., Page, E. C., François, M., Hughes, T. P., Yeung, D. & White, D. L., Aug 2022, In: Cancer Gene Therapy. 29, 8-9, p. 1140-1152 13 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• HMGN1 plays a significant role in CRLF2 driven Down Syndrome leukemia and provides a potential therapeutic target in this high-risk cohort

  Page, E. C., Heatley, S. L., Eadie, L. N., McClure, B. J., de Bock, C. E., Omari, S., Yeung, D., Hughes, T., Thomas, P. & White, D., 4 Feb 2022, In: Oncogene. 41, 6, p. 797-808 12 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions

  Venn, N. C., Huang, L., Hovorková, L., Muskovic, W., Wong, M., Law, T., Heatley, S. L., Khaw, S. L., Revesz, T., Dalla Pozza, L., Shaw, P. J., Fraser, C., Moore, A. S., Cross, S., Bendak, K., Norris, M. D., Henderson, M. J., White, D. L., Cowley, M. J. & Trahair, T. N. & 2 others, Zuna, J. & Sutton, R., 2022, (Accepted/In press) In: British Journal of Cancer.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Multi-Cohort Transcriptomic Subtyping of B-Cell Acute Lymphoblastic Leukemia

  Mäkinen, V. P., Rehn, J., Breen, J., Yeung, D. & White, D. L., 1 May 2022, In: International Journal of Molecular Sciences. 23, 9, 4574.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Citations (Scopus)

• Optimizing antifungal prophylaxis in allogeneic stem cell transplantation: A cohort study of two different approaches

  Selby, P. R., Warner, M. S., Peake, S. L., Bardy, P., Hiwase, D., Singhal, D., Beligaswatte, A., Hahn, U., Roberts, J. A., Yeung, D. & Shakib, S., Dec 2022, In: Transplant Infectious Disease. 24, 6, e13988.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)

• RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL)

  Rehn, J., Mayoh, C., Heatley, S. L., McClure, B. J., Eadie, L. N., Schutz, C., Yeung, D. T., Cowley, M. J., Breen, J. & White, D. L., 17 Oct 2022, In: PLoS Genetics. 18, 10, e1010300.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Citations (Scopus)

• RNA-Based Targeted Gene Sequencing Improves the Diagnostic Yield of Mutant Detection in Chronic Myeloid Leukemia

  Shanmuganathan, N., Wadham, C., Thomson, D., Shahrin, N. H., Vignaud, C., Obourn, V., Chaturvedi, S., Yang, F., Feng, J., Saunders, V., Kok, C. H., Yeung, D., King, R. M., Kenyon, R. R., Lin, M., Wang, P., Scott, H., Hughes, T., Schreiber, A. W. & Branford, S., Jul 2022, In: Journal of Molecular Diagnostics. 24, 7, p. 803-822 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Citations (Scopus)

• Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants

  Australasian Consortium for RNA Diagnostics, Jan 2022, In: Genetics in Medicine. 24, 1, p. 130-145 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  51 Citations (Scopus)
• 2021

  Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia

  Downes, C. E. J., McClure, B. J., Bruning, J. B., Page, E., Breen, J., Rehn, J., Yeung, D. & White, D., Dec 2021, In: NPJ precision oncology. 5, 1, 75.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• CKLF and IL1B transcript levels at diagnosis are predictive of relapse in children with pre-B-cell acute lymphoblastic leukaemia

  Fitter, S., Bradey, A. L., Kok, C. H., Noll, J. E., Wilczek, V. J., Venn, N. C., Law, T., Paisitkriangkrai, S., Story, C., Saunders, L., Dalla Pozza, L., Marshall, G. M., White, D. L., Sutton, R., Zannettino, A. C. W. & Revesz, T., Apr 2021, In: British Journal of Haematology. 193, 1, p. 171-175 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Constitutive JAK/STAT signaling is the primary mechanism of resistance to JAKi in TYK2-rearranged acute lymphoblastic leukemia

  Tavakoli Shirazi, P., Eadie, L. N., Page, E. C., Heatley, S. L., Bruning, J. B. & White, D. L., 1 Aug 2021, In: Cancer Letters. 512, p. 28-37 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia

  El Khawanky, N., Hughes, A., Yu, W., Myburgh, R., Matschulla, T., Taromi, S., Aumann, K., Clarson, J., Vinnakota, J. M., Shoumariyeh, K., Miething, C., Lopez, A. F., Brown, M. P., Duyster, J., Hein, L., Manz, M. G., Hughes, T. P., White, D. L., Yong, A. S. M. & Zeiser, R., Dec 2021, In: Nature Communications. 12, 1, 6436.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  61 Citations (Scopus)

• Early BCR-ABL1 kinetics are predictive of subsequent achievement of treatment-free remission in chronic myeloid leukemia

  Shanmuganathan, N., Pagani, I. S., Ross, D. M., Park, S., Yong, A. S. M., Braley, J. A., Altamura, H. K., Hiwase, D. K., Yeung, D. T., Kim, D. W., Branford, S. & Hughes, T. P., 4 Mar 2021, In: Blood. 137, 9, p. 1196-1207 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  55 Citations (Scopus)

• Identification of a novel GOLGA4-JAK2 fusion gene in B-cell acute lymphoblastic leukaemia

  Downes, C. E. J., Rehn, J., Heatley, S. L., Yeung, D., McClure, B. J. & White, D. L., 25 Oct 2021, (E-pub ahead of print) In: British Journal of Haematology.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• In-vitro modeling of TKI resistance in the high-risk B-cell acute lymphoblastic leukemia fusion gene RANBP2-ABL1 - implications for targeted therapy

  Heatley, S. L., Asari, K., Schutz, C. E., Leclercq, T. M., McClure, B. J., Eadie, L. N., Hughes, T. P., Yeung, D. T. & White, D. L., 2021, In: Leukemia and Lymphoma. 62, 5, p. 1157-1166 10 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab

  Sutton, R., Pozza, L. D., Khaw, S. L., Fraser, C., Revesz, T., Chamberlain, J., Mitchell, R., Trahair, T. N., Bateman, C. M., Venn, N. C., Law, T., Ong, E., Heatley, S. L., McClure, B. J., Meyer, C., Marschalek, R., Henderson, M. J., Cross, S., White, D. L. & Kotecha, R. S., May 2021, In: Pediatric Blood and Cancer. 68, 5, e28922.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells

  García-Montolio, M., Ballaré, C., Blanco, E., Gutiérrez, A., Aranda, S., Gómez, A., Kok, C. H., Yeung, D. T., Hughes, T. P., Vizán, P. & Di Croce, L., 29 Apr 2021, In: Frontiers in Cell and Developmental Biology. 9, 655201.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Simvastatin enhances the efficacy of nilotinib in chronic myeloid leukaemia by post-translational modification and drug transporter modulation

  Asari, K., Sun, W. T., Kok, Z. H., Lam, Y. H., Ng, B. L., Saunders, V., White, D. L., Chuah, C. & Xiang, W., 1 Jun 2021, In: Anti-Cancer Drugs. 32, 5, p. 526-536 11 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

  Blake, S. J., James, J., Ryan, F. J., Caparros-Martin, J., Eden, G. L., Tee, Y. C., Salamon, J. R., Benson, S. C., Tumes, D. J., Sribnaia, A., Stevens, N. E., Finnie, J. W., Kobayashi, H., White, D. L., Wesselingh, S. L., O'Gara, F., Lynn, M. A. & Lynn, D. J., 21 Dec 2021, In: Cell Reports Medicine. 2, 12, 100464.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Citations (Scopus)

• TYK2 activating alterations in acute lymphoblastic leukaemia: Novel driver oncogenes with potential avenues for precision medicine

  Tavakoli Shirazi, P., Eadie, L., Heatley, S. & White, D., 2021, In: Journal of Cancer Science and Clinical Therapeutics.

  Research output: Contribution to journal › Article › peer-review

• Understanding the Role of Chromosome 21 for Precision Treatment in Down Syndrome Acute Lymphoblastic Leukaemia

  Page, E. C. & White, D., 16 Jan 2021, In: Journal of Alzheimers Disease & Parkinsonism.

  Research output: Contribution to journal › Article › peer-review
• 2020

  Chronic leukaemias in the community

  Li, E. W., Yeung, D. & Fuller, S., Aug 2020, In: Australian Prescriber. 43, 4, p. 126-130 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Clinical Effectiveness of Conjugate Pneumococcal Vaccination in Hematopoietic Stem Cell Transplantation Recipients

  Roberts, M. B., Bak, N., Wee, L. Y. A., Chhetri, R., Yeung, D. T., Lewis, I. & Hiwase, D. K., Feb 2020, In: Biology of Blood and Marrow Transplantation. 26, 2, p. 421-427 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Citations (Scopus)

• Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission

  Pagani, I. S., Dang, P., Saunders, V. A., Grose, R., Shanmuganathan, N., Kok, C. H., Carne, L., Rwodzi, Z., Watts, S., McLean, J., Braley, J., Altamura, H., Yeung, D. T., Branford, S., Yong, A. S. M., White, D. L., Hughes, T. P. & Ross, D. M., Apr 2020, In: Leukemia. 34, 4, p. 1052-1061 10 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study

  Bloor, A. J. C., Patel, A., Griffin, J. E., Gilleece, M. H., Radia, R., Yeung, D. T., Drier, D., Larson, L. S., Uenishi, G. I., Hei, D., Kelly, K., Slukvin, I. & Rasko, J. E. J., Nov 2020, In: Nature Medicine. 26, 11, p. 1720-1725 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  204 Citations (Scopus)

• Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols

  Cario, G., Leoni, V., Conter, V., Attarbaschi, A., Zaliova, M., Sramkova, L., Cazzaniga, G., Fazio, G., Sutton, R., Elitzur, S., Izraeli, S., Lauten, M., Locatelli, F., Basso, G., Buldini, B., Bergmann, A. K., Lentes, J., Steinemann, D., Göhring, G. & Schlegelberger, B. & 15 others, Haas, O. A., Schewe, D., Buchmann, S., Moericke, A., White, D., Revesz, T., Stanulla, M., Mann, G., Bodmer, N., Arad-Cohen, N., Zuna, J., Valsecchi, M. G., Zimmermann, M., Schrappe, M. & Biondi, A., 1 Jul 2020, In: Haematologica. 105, 7, p. 1887-1894 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  38 Citations (Scopus)

• Successful treatment-free remission in chronic myeloid leukaemia and its association with reduced immune suppressors and increased natural killer cells

  Irani, Y. D., Hughes, A., Clarson, J., Kok, C. H., Shanmuganathan, N., White, D. L., Yeung, D. T., Ross, D. M., Hughes, T. P. & Yong, A. S. M., 1 Nov 2020, In: British Journal of Haematology. 191, 3, p. 433-441 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  54 Citations (Scopus)

• Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukaemia patients

  Schmitz, U., Shah, J. S., Dhungel, B. P., Monteuuis, G., Luu, P. L., Petrova, V., Metierre, C., Nair, S. S., Bailey, C. G., Saunders, V. A., Turhan, A. G., White, D. L., Branford, S., Clark, S. J., Hughes, T. P., Wong, J. J. L. & Rasko, J. E. J., Dec 2020, In: Cancers. 12, 12, p. 1-19 19 p., 3738.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Citations (Scopus)
• 2019

  Asciminib in chronic myeloid leukemia after Abl kinase inhibitor failure

  Hughes, T. P., Mauro, M. J., Cortes, J. E., Minami, H., Rea, D., DeAngelo, D. J., Breccia, M., Goh, Y. T., Talpaz, M., Hochhaus, A., Coutre, P. L., Ottmann, O., Heinrich, M. C., Steegmann, J. L., Deininger, M. W. N., Janssen, J. J. W. M., Mahon, F. X., Minami, Y., Yeung, D. & Ross, D. M. & 10 others, Tallman, M. S., Park, J. H., Druker, B. J., Hynds, D., Duan, Y., Meille, C., Hourcade-Potelleret, F., Vanasse, K. G., Lang, F. & Kim, D. W., 12 Dec 2019, In: New England Journal of Medicine. 381, 24, p. 2315-2326 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  306 Citations (Scopus)