Research output per year
Research output per year
Personal profile
Public Profile
Dr Grundy is an emerging leader in the field of Neurourology, having established an internationally recognised research program identifying the functional classes of afferents that innervate the bladder, and the channels and receptors underlying their function in health and chronic pain states. His research focuses on understanding the mechanisms that regulate sensory neurons that provide sensations from the bladder and the bacteria that cause urinary tract infections. Dr Grundy has a proven track record, with high impact publications in journals such as Nature, Pain, JCI insight, Scientific Reports, and the American Journal of Physiology. He also has invited reviews published in Annual Reviews of Physiology, American Journal of Phsyiology, and Frontiers in Autonomic Neuroscience.
Education/Academic qualification
PhD, Bond University
Award Date: 30 Sep 2014
Bachelor of Science (Honours), University of Nottingham
Award Date: 15 Jun 2007
External positions
Research Fellow, Flinders University
Aug 2019 → …
Keywords
- Bladder
- Colon
- Pelvic Pain
- Visceral Pain
- Urinary Tract Infection
- Chronic pain
- Electrophysiology
- Sensation
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A syngeneic inoculation mouse model of endometriosis that develops multiple comorbid visceral and cutaneous pain like behaviours
Maddern, J., Grundy, L., Harrington, A., Schober, G., Castro, J. & Brierley, S. M., 1 Aug 2022, In: Pain. 163, 8, p. 1622-1635 14 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
TGR5 agonists induce peripheral and central hypersensitivity to bladder distension
Caldwell, A., Grundy, L., Harrington, A. M., Garcia-Caraballo, S., Castro, J., Bunnett, N. W. & Brierley, S. M., 15 Jun 2022, In: Scientific reports. 12, 1, 9920.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
The T type calcium channel CaV3.2 regulates bladder afferent responses to mechanical stimuli
Grundy, L., Tay, C., Christie, S., Harrington, A. M., Castro, J., Cardoso, F. C., Lewis, R. J., Zagorodnyuk, V. & Brierley, S. M., 21 Oct 2022, (E-pub ahead of print) In: Pain.Research output: Contribution to journal › Article › peer-review
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Urinary tract infection in overactive bladder: an update on pathophysiological mechanisms
Mansfield, K. J., Chen, Z., Moore, K. H. & Grundy, L., 4 Jul 2022, In: Frontiers in Physiology. 13, 886782.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Activation of MrgprA3 and MrgprC11 on bladder-innervating afferents induces peripheral and central hypersensitivity to bladder distension
Grundy, L., Caldwell, A., Garcia-Caraballo, S., Grundy, D., Spencer, N. J., Dong, X., Castro, J., Harrington, A. M. & Brierley, S. M., 28 Apr 2021, In: Journal of Neuroscience. 41, 17, p. 3900-3916 17 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus)
Activities
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Mechanisms Underlying Bladder Sensation in Health and Disease
Luke Grundy (Speaker)
10 Sep 2021Activity: Invited talks and oral presentations › Invited Keynote and Plenary Presentations
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Bladders Under Siege
Luke Grundy (Speaker)
14 Oct 2021 → 17 Oct 2021Activity: Invited talks and oral presentations › Oral conference presentations and other invited talks
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Mechanisms of bladder sensation
Luke Grundy (Speaker)
18 Apr 2021Activity: Invited talks and oral presentations › Oral conference presentations and other invited talks
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Mechanisms Underlying Bladder Induced Pain
Luke Grundy (Speaker)
11 Apr 2021Activity: Invited talks and oral presentations › Oral conference presentations and other invited talks
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Unravelling bladder sensory mechanisms in health and disease
Luke Grundy (Speaker)
4 Oct 2021Activity: Invited talks and oral presentations › Oral conference presentations and other invited talks