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20142025

Research activity per year

Personal profile

Public Profile

Dr Noralyn Mañucat-Tan is a biomedical scientist with expertise in cellular biochemistry, neuroscience, and translational disease research. Her work focuses on uncovering the molecular mechanisms that drive complex diseases, spanning lipid metabolism, neurodegeneration, and cancer biology. She completed her master’s degree in Cellular Biochemistry at Kyoto University, where she studied the interactions of ApoA-1, ATP-binding cassette transporters and fatty acids in cholesterol transport. In 2017, she obtained her PhD in Medical Sciences from the University of South Australia with a focus on neurodegenerative disease mechanisms involved in the activity of neutrotrophin receptor, p75NTR in Alzheimer's Disease and Frontotemporal Lobar Degeneration. She later continued her work on amyloid beta as a postdoctoral researcher at Flinders University, where she investigated mechanisms on how amyloid beta is influenced by oxidative stress pathways. In 2023, she joined Prof. Jordan Hansford's research team in the Paediatric Neuro-Oncology Laboratory at the South Australia Health and Medical Research Institute (SAHMRI). Her current research integrates multi-omics and advanced disease models to improve understanding of paediatric brain cancers and other devastating diseases.

Education/Academic qualification

PhD, A role of p75NTR in neurodegeneration in Alzheimer's Disease and Tauopathy, University of South Australia

15 Jul 201319 Oct 2017

Award Date: 19 Oct 2017

Masters, Effects of Unsaturated Fatty Acids on ABC-mediated cholesterol homeostasis, Kyoto University

1 Apr 201125 Mar 2013

Award Date: 25 Mar 2013

Bachelor's Degree, Stability of Alugbati (Basella rubra) Anthocyanin, University of the Philippines

Award Date: 27 Apr 2008

External positions

Scientist, Women's and Children's Hospital

17 Jun 2023 → …

Postdoctoral Researcher, Flinders University

5 Mar 200831 Oct 2023

Keywords

  • paediatric brain cancer; genomic biomarkers, epigenomic biomarker, cancer survivorship; neurodegeneration

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or