Research output per year
Research output per year
Personal profile
Public Profile
Ryan’s early research career has focused on understanding the pathophysiology of secondary degeneration following neurotrauma to the central nervous system (CNS). He uses innovative analytical techniques to demonstrate biochemical, molecular and gross anatomical changes that occur following CNS injury. Ryan has developed and optimised a combinatorial treatment strategy incorporating pharmacotherapeutics for the treatment of CNS injury. Ryan’s combinatorial strategy has been assessed in a clinically relevant model of spinal cord injury (SCI), demonstrating significant functional recovery and tissue sparing, crucial for the translation of his research into clinical trials.
In 2017, Ryan joined the SAHMRI Mind & Brain team in collaboration with Project Discovery and the Neil Sachse Centre for Spinal Cord Research, to provide his expertise in SCI and other neurotrauma models. Ryan looks to help develop new techniques to provide a more accurate diagnosis and prognosis of SCI, to identify potential treatment strategies in a clinical setting.
Research Interests
- Neurotrauma
- Neuropharmacology
- Molecular Biology
- Glia
- Oxidative stress
- Calcium dynamics
- Nuclear Imaging
- MRI
Education/Academic qualification
Bachelor's Degree, University of Western Australia
Bachelor's Degree (Honours), University of Western Australia
PhD, University of Western Australia
External positions
Adjunct Lecturer, University of Adelaide
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Complementing neuroregeneration: deciphering the role of neuro-immune interactions in CNS repair
Jenkner, S. & O'Hare Doig, R., 6 Apr 2022, In: Journal of Neuroscience. 42, 14, p. 2850-2852 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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Survival model of thoracic contusion spinal cord injury in the domestic pig
Gayen, C., Bessen, M. A., Dorrian, R., Quarrington, R. D., Mulaibrahimovic, A., O'Hare Doig, R., Freeman, B. J. C., Leonard, A. V. & Jones, C. F., 15 Nov 2022, (E-pub ahead of print) In: Journal of Neurotrauma.Research output: Contribution to journal › Article › peer-review
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Biodegradable and biocompatible graphene-based scaffolds for functional neural tissue engineering: a strategy approach using dental pulp stem cells and biomaterials.
Mansouri, N., Al-Sarawi, S., Losic, D., Mazumdar, J., Clark, J., Gronthos, S. & O'Hare Doig, R., 15 Jul 2021, (E-pub ahead of print) In: Biotechnology and Bioengineering.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Acute cellular and functional changes with a combinatorial treatment of ion channel inhibitors following spinal cord injury
O'Hare Doig, R. L., Santhakumar, S., Fehily, B., Raja, S., Solomon, T., Bartlett, C. A., Fitzgerald, M. & Hodgetts, S. I., 2020, In: Frontiers in molecular neuroscience. 13, p. 85Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
18-kDa translocator protein radioligand [18F]GE-180 as a diagnostic and prognostic biomarker following spinal cord injury
O'Hare Doig, R., Lewis, M., Keller, M., Clark, J., Jones, C. & Freeman, B. J. C., 2018.Research output: Contribution to conference › Poster › peer-review
Prizes
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Australian Postgraduate Award (Scholarship)
O'Hare Doig, Ryan (Recipient), 2013
Prize: Other distinction
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Activities
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Australian Society of Molecular Imaging Symposium
Johan Verjans (Organiser), Sally E. Plush (Organiser), Ryan O'Hare Doig (Organiser), Patrick Hughes (Organiser), Nicole Dmochowska (Organiser) & Marianne Keller (Organiser)
7 Nov 2019 → 8 Nov 2019Activity: Participating in or organising an event › Organising a conference
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International Journal of Peptide Research and Therapeutics (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review
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Translational Neuroscience (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review
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Life Sciences (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → 2019Activity: Publication peer-review and formal editorial roles › Publication peer-review
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Experimental Neurology (Journal)
Ryan O'Hare Doig (Reviewer)
2018 → …Activity: Publication peer-review and formal editorial roles › Publication peer-review