Personal profile
Public Profile
Associate Professor Sang Hong Lee (Hong Lee) is the leader of the statistical genetics group at the Australian Centre for Precision Health at University of South Australia. He graduated from Dong-A University in S. Korea (Bachelor in 1998) and University of New England (PhD in 2006). Dr Lee has extensive experience in developing advanced statistical methods to estimate genetic variance and individual genetic effects based on phenotype-genotype association analyses. Currently, Dr Lee is focusing on understanding the genetic architecture of complex traits by tackling G x E interaction using advanced statistical models. His developed models and methods have been also widely used across multidisciplinary fields including human genetics, animal and plant breeding, evolutionary genetics and social and behavior science. The total number of his publications is > 100 that have ~27,000 citations to date and h-index 56.
Education/Academic qualification
PhD, Fine mapping of quantitative trait loci : statistical development and application in livestock, University of New England
10 Feb 2002 → 7 Apr 2006
Award Date: 7 Apr 2006
Masters, University of New England
10 Feb 2001 → 1 Feb 2002
Award Date: 1 Feb 2002
Keywords
- precision medicine
- Statistical Methodology and Modelling
- Genome-wide association
- Genomics
- Mental Health
- Cancer Genomics
Collaborations and top research areas from the last five years
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Cross-Ancestry Polygenic Prediction: Comparing Methods and Assessing Transferability Across Traits
Momin, M. M., Zhou, X., Ahmed, M., Hyppönen, E., Benyamin, B. & Lee, S. H., Feb 2026, In: Genetic Epidemiology. 50, 1, e70029.Research output: Contribution to journal › Article › peer-review
Open Access -
Leveraging polygenic risk scores to infer causal directions in genotype-by-environment interactions between complex traits
Fentaw, Z., Truong, B., Jayasinghe, D., Vedova, C. D., Hemani, G., Benyamin, B., Hyppönen, E. & Lee, S. H., Dec 2026, In: Human Genetics. 145, 1, 19.Research output: Contribution to journal › Article › peer-review
Open Access -
Phenome-wide study on alcohol consumption provides genetic evidence for a causal association with multiple diseases and biomarkers
Assefa Kassaw, N., Zhou, A., Stacey, D., Mulugeta, A., Lee, S. H., Burgess, S. & Hyppӧnen, E., Jan 2026, (Accepted/In press) In: Nutrition, Metabolism and Cardiovascular Diseases. 104624.Research output: Contribution to journal › Article › peer-review
Open Access -
The differences in sex ratio between sporadic and familial amyotrophic lateral sclerosis: a systematic review
Boomsma, A., Doyle, C., Sai, N., Rogers, M. L., Lee, S. H. & Benyamin, B., Feb 2026, In: Journal of Neurology. 273, 2, 92.Research output: Contribution to journal › Article › peer-review
Open Access -
A latent outcome variable approach for Mendelian randomization using the stochastic expectation maximization algorithm
Amente, L. D., Mills, N. T., Le, T. D., Hyppönen, E. & Lee, S. H., May 2025, In: Human Genetics. 144, 5, p. 559-574 16 p., k601.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus)