A demonstration of multiplex biosensing using whispering gallery mode microspheres positioned onto a microstructured optical fiber tip

T. Reynolds, A. François, S. J. Nicholls, T. M. Monro

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Citations (Scopus)

Abstract

Here, we show that multiplexed Whispering Gallery Modes sensing can be achieved using two dye-doped microspheres positioned onto the tip of a Microstructured Optical Fiber. By operating the dye-doped microspheres below their lasing threshold, the individual resonances of each sphere overlap and therefore cannot be distinguished. However, when excited above their lasing threshold results in a de-convoluted spectrum where the resonances belonging to the individual spheres can be determined, enabling the detection of a specific interaction in one resonator and using the second as a dynamic reference, or monitoring different specific interactions with both spheres.

Original languageEnglish
Title of host publicationOptical Diagnostics and Sensing XIV
Subtitle of host publicationToward Point-of-Care Diagnostics
PublisherSPIE
ISBN (Print)9780819498649
DOIs
Publication statusPublished or Issued - 2014
EventOptical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics - San Francisco, CA, United States
Duration: 3 Feb 20146 Feb 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8951
ISSN (Print)1605-7422

Other

OtherOptical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics
Country/TerritoryUnited States
CitySan Francisco, CA
Period3/02/146/02/14

Keywords

  • Biosensors
  • Microstructured Optical Fiber
  • Multiplexing
  • Whispering Gallery Modes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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