Acute myocardial infarction: Early treatment

Philip Aylward

Research output: Contribution to journalShort surveypeer-review

6 Citations (Scopus)


Acute myocardial infarction is a common cause of death. Most of the deaths are due to ventricular fibrillation occurring soon after the onset of ischaemia. Once the patient reaches hospital, the major aim of treatment is to decrease the size of the infarct. Fibrinolytic therapy with streptokinase or tissue plasminogen activator (tPA) restores coronary patency and significantly reduces mortality. Aspirin is mandatory unless there are absolute contraindications to its use. Heparin is optional with streptokinase but necessary with tPA. ACE inhibitors and intravenous beta blockers are beneficial in acute myocardial infarction and intravenous glyceryl trinitrate probably has a role. Calcium channel blockers and magnesium should not be used routinely.

Original languageEnglish
Pages (from-to)52-54
Number of pages3
JournalAustralian Prescriber
Issue number2
Publication statusPublished or Issued - 1 Jan 1996
Externally publishedYes


  • ACE inhibitors
  • anticoagulation
  • aspirin
  • fibrinolytic therapy

ASJC Scopus subject areas

  • Pharmacology (medical)

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