An assessment of different filter systems for extracorporeal elimination of bivalirudin: An in vitro study

Andreas Koster; Derek Chew; Marcus Gründel; Harald Hausmann; Onnen Grauhan; Herman Kuppe; Bruce D. Spiess

doi:10.1213/01.ANE.0000057605.61063.55

An assessment of different filter systems for extracorporeal elimination of bivalirudin: An in vitro study

Andreas Koster, Derek Chew, Marcus Gründel, Harald Hausmann, Onnen Grauhan, Herman Kuppe, Bruce D. Spiess

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

Bivalirudin is a new, direct thrombin inhibitor. We investigated the extracorporeal elimination rate of different hemofilters and one plasmapheresis filter for bivalirudin. Our data show that bivalirudin can be effectively eliminated via hemofiltration and plasmapheresis, although there were significant differences in the elimination rates among the filter systems investigated.

Original language	English
Pages (from-to)	1316-1319
Number of pages	4
Journal	Anesthesia and Analgesia
Volume	96
Issue number	5
DOIs	https://doi.org/10.1213/01.ANE.0000057605.61063.55
Publication status	Published or Issued - 1 May 2003
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1213/01.ANE.0000057605.61063.55

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AU - Koster, Andreas

AU - Chew, Derek

AU - Gründel, Marcus

AU - Hausmann, Harald

AU - Grauhan, Onnen

AU - Kuppe, Herman

AU - Spiess, Bruce D.

PY - 2003/5/1

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AB - Bivalirudin is a new, direct thrombin inhibitor. We investigated the extracorporeal elimination rate of different hemofilters and one plasmapheresis filter for bivalirudin. Our data show that bivalirudin can be effectively eliminated via hemofiltration and plasmapheresis, although there were significant differences in the elimination rates among the filter systems investigated.

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An assessment of different filter systems for extracorporeal elimination of bivalirudin: An in vitro study

Abstract

ASJC Scopus subject areas

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