An assessment of different filter systems for extracorporeal elimination of bivalirudin: An in vitro study

Andreas Koster, Derek Chew, Marcus Gründel, Harald Hausmann, Onnen Grauhan, Herman Kuppe, Bruce D. Spiess

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)


Bivalirudin is a new, direct thrombin inhibitor. We investigated the extracorporeal elimination rate of different hemofilters and one plasmapheresis filter for bivalirudin. Our data show that bivalirudin can be effectively eliminated via hemofiltration and plasmapheresis, although there were significant differences in the elimination rates among the filter systems investigated.

Original languageEnglish
Pages (from-to)1316-1319
Number of pages4
JournalAnesthesia and Analgesia
Issue number5
Publication statusPublished or Issued - 1 May 2003
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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