@article{6c42d2837d1c4604bee1e7dfbcfd7c78,
title = "Antenatal magnesium individual participant data international collaboration: Assessing the benefits for babies using the best level of evidence (AMICABLE)",
abstract = "Background: The primary aim of this study is to assess, using individual participant data (IPD) meta-analysis, the effects of administration of antenatal magnesium sulphate given to women at risk of preterm birth on important clinical outcomes for their child such as death and neurosensory disability. The secondary aim is to determine whether treatment effects differ depending on important pre-specified participant and treatment characteristics, such as reasons at risk of preterm birth, gestational age, or type, dose and mode of administration of magnesium sulphate.Methods: Discussion: Results are expected to be publicly available in 2012.",
keywords = "Cerebral palsy, Individual patient data, Magnesium sulphate, Meta-analysis, Preterm birth",
author = "Crowther, {C. A.} and Middleton, {P. F.} and Askie, {L. M.} and Doyle, {L. W.} and Bubner, {T. K.} and M. Voysey",
note = "Funding Information: The AMICABLE Group The AMICABLE IPD Project Team: CA Crowther1 (chair), PF Middleton1 (epidemiologist), LM Askie2 (advice on IPD methodology), LW Doyle3 (advice on paediatric aspects), TK Bubner1 (project coordinator), M Voysey4 (AMICABLE coordinating statistician). 1Australian Research Centre for Health of Women and Babies, Discipline of Obstetrics and Gynaecology, The University of Adelaide, Australia 2NHMRC Clinical Trials Centre, University of Sydney, Australia 3Department of Obstetrics and Gynaecology, University of Melbourne, Australia 4Centre for Statistics in Medicine, University of Oxford, United Kingdom The AMICABLE Data Management Group (as at 11/8/11): M Voysey (coordinating statistician), L Yelland (participating trial statistician), S Zhang (data management centre). The AMICABLE Trialist Group (as at 11/8/2011): Australasian Collaborative Trial of Magnesium Sulphate (ACTOMgSO4): CA Crowther, LW Doyle; MAGnesium sulphate for Prevention of Eclampsia (MAGPIE): LW Duley, D Altman; Magnesium sulfate given before very pre-term birth (PREMAG): S Marret, L Marpeau, C Leveque; Magnesium and Neurologic Endpoints Trial (MAGNET): R Mittendorf, P Pryde. The AMICABLE IPD Study is funded by a project grant from the Australian National Health and Medical Research Council (NHMRC) which will support the collection of the IPD by the original investigators, data management and the analyses and the collaborators{\textquoteright} meetings. The NHMRC is not involved in any other aspect of the project, such as the design of the project{\textquoteright}s protocol and analysis plan, the collection and the analyses of the project{\textquoteright}s data, or the interpretation and the publication of the study results.",
year = "2012",
month = mar,
day = "21",
doi = "10.1186/2046-4053-1-21",
language = "English",
volume = "1",
journal = "Systematic reviews",
issn = "2046-4053",
publisher = "BioMed Central",
number = "1",
}