ATG8ylation of proteins: A way to cope with cell stress?

Julian M. Carosi; Thanh N. Nguyen; Michael Lazarou; Sharad Kumar; Timothy J. Sargeant

doi:10.1083/jcb.202108120

ATG8ylation of proteins: A way to cope with cell stress?

Julian M. Carosi, Thanh N. Nguyen, Michael Lazarou, Sharad Kumar, Timothy J. Sargeant

Lysosomal Health In Ageing

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.

Original language	English
Article number	e202108120
Journal	Journal of Cell Biology
Volume	220
Issue number	11
DOIs	https://doi.org/10.1083/jcb.202108120
Publication status	Published or Issued - 1 Nov 2021

ASJC Scopus subject areas

Cell Biology

Access to Document

10.1083/jcb.202108120

Cite this

@article{eaed8b26c3d94bcdad79b1e01a873ce4,

title = "ATG8ylation of proteins: A way to cope with cell stress?",

abstract = "The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.",

author = "Carosi, \{Julian M.\} and Nguyen, \{Thanh N.\} and Michael Lazarou and Sharad Kumar and Sargeant, \{Timothy J.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Carosi et al.",

year = "2021",

month = nov,

day = "1",

doi = "10.1083/jcb.202108120",

language = "English",

volume = "220",

journal = "Journal of Cell Biology",

issn = "0021-9525",

publisher = "Rockefeller University Press",

number = "11",

}

TY - JOUR

T1 - ATG8ylation of proteins

T2 - A way to cope with cell stress?

AU - Carosi, Julian M.

AU - Nguyen, Thanh N.

AU - Lazarou, Michael

AU - Kumar, Sharad

AU - Sargeant, Timothy J.

PY - 2021/11/1

Y1 - 2021/11/1

N2 - The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.

AB - The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.

UR - https://www.scopus.com/pages/publications/85119103936

U2 - 10.1083/jcb.202108120

DO - 10.1083/jcb.202108120

M3 - Article

C2 - 34671813

AN - SCOPUS:85119103936

SN - 0021-9525

VL - 220

JO - Journal of Cell Biology

JF - Journal of Cell Biology

IS - 11

M1 - e202108120

ER -

ATG8ylation of proteins: A way to cope with cell stress?

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this