Burning Fat Fuels Leukemic Stem Cell Heterogeneity

Daniel Thomas; Ravindra Majeti

doi:10.1016/j.stem.2016.06.014

Burning Fat Fuels Leukemic Stem Cell Heterogeneity

Daniel Thomas, Ravindra Majeti

Research output: Contribution to journal › Short survey › peer-review

7 Citations (Scopus)

Abstract

Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Cell Stem Cell
Volume	19
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2016.06.014
Publication status	Published or Issued - 1 Jul 2016
Externally published	Yes

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

Access to Document

10.1016/j.stem.2016.06.014

Cite this

@article{c034ff7014e2406a98fc06c7cf9e5641,

title = "Burning Fat Fuels Leukemic Stem Cell Heterogeneity",

abstract = "Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.",

author = "Daniel Thomas and Ravindra Majeti",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = jul,

day = "1",

doi = "10.1016/j.stem.2016.06.014",

language = "English",

volume = "19",

pages = "1--2",

journal = "Cell Stem Cell",

issn = "1934-5909",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - Burning Fat Fuels Leukemic Stem Cell Heterogeneity

AU - Thomas, Daniel

AU - Majeti, Ravindra

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.

AB - Obese leukemia patients exhibit reduced survival after chemotherapy, suggesting an important role of adipose tissue in disease progression. In this issue of Cell Stem Cell, Ye et al. (2016) reveal metabolic heterogeneity in leukemic stem cell (LSC) subpopulations and show that chemotherapy-resistant CD36+ LSCs co-opt gonadal adipose tissue to support their metabolism and survival.

UR - https://www.scopus.com/pages/publications/85008894497

U2 - 10.1016/j.stem.2016.06.014

DO - 10.1016/j.stem.2016.06.014

M3 - Short survey

C2 - 27392217

AN - SCOPUS:85008894497

SN - 1934-5909

VL - 19

SP - 1

EP - 2

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 1

ER -

Burning Fat Fuels Leukemic Stem Cell Heterogeneity

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this