Cardiac hemodynamics in men versus women during acute ST-segment elevation myocardial infarction

R. P. Dreyer; J. F. Beltrame; C. Neil; T. Air; R. Tavella; B. Hoffmann; P. K. Pati; D. Di Fiore; M. Arstall; C. Zeitz

doi:10.1016/j.amjcard.2013.03.007

Cardiac hemodynamics in men versus women during acute ST-segment elevation myocardial infarction

R. P. Dreyer
, J. F. Beltrame
, C. Neil
, T. Air
, R. Tavella
, B. Hoffmann
, P. K. Pati
, D. Di Fiore
, M. Arstall
, C. Zeitz

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Several biologic and clinical factors contribute to the increased 30-day mortality and re-infarction rate in women with ST-segment elevation myocardial infarction (STEMI). Sex differences in cardiac hemodynamic parameters such as pulmonary capillary wedge pressure (PCWP) have not been examined and might play an important role. The objectives of the present study were to examine whether female sex is an independent determinant of PCWP during acute STEMI and whether an elevated PCWP contributes to all-cause 30-day mortality and re-infarction in women. The clinical, angiographic, and hemodynamic features of 470 consecutive patients with STEMI (n = 135 women) undergoing emergency coronary angiography with right-side heart catheterization were evaluated with respect to sex. Women had an elevated PCWP (20 +/- 8 vs 16 +/- 7 mm Hg, p

Original language	English
Pages (from-to)	143-149
Number of pages	7
Journal	Cardiology research
Volume	112
Issue number	2
DOIs	https://doi.org/10.1016/j.amjcard.2013.03.007
Publication status	Published or Issued - 2013
Externally published	Yes

Keywords

Aged Cohort Studies Electrocardiography Female *Hemodynamics Humans Male Middle Aged Myocardial Infarction/mortality/*physiopathology Pulmonary Wedge Pressure Recurrence Sex Factors

Access to Document

10.1016/j.amjcard.2013.03.007

https://www.ncbi.nlm.nih.gov/pubmed/23628307

Cite this

@article{19476690b12c4be4aad3196660719811,

title = "Cardiac hemodynamics in men versus women during acute ST-segment elevation myocardial infarction",

abstract = "Several biologic and clinical factors contribute to the increased 30-day mortality and re-infarction rate in women with ST-segment elevation myocardial infarction (STEMI). Sex differences in cardiac hemodynamic parameters such as pulmonary capillary wedge pressure (PCWP) have not been examined and might play an important role. The objectives of the present study were to examine whether female sex is an independent determinant of PCWP during acute STEMI and whether an elevated PCWP contributes to all-cause 30-day mortality and re-infarction in women. The clinical, angiographic, and hemodynamic features of 470 consecutive patients with STEMI (n = 135 women) undergoing emergency coronary angiography with right-side heart catheterization were evaluated with respect to sex. Women had an elevated PCWP (20 +/- 8 vs 16 +/- 7 mm Hg, p ",

keywords = "Aged Cohort Studies Electrocardiography Female *Hemodynamics Humans Male Middle Aged Myocardial Infarction/mortality/*physiopathology Pulmonary Wedge Pressure Recurrence Sex Factors",

author = "Dreyer, \{R. P.\} and Beltrame, \{J. F.\} and C. Neil and T. Air and R. Tavella and B. Hoffmann and Pati, \{P. K.\} and \{Di Fiore\}, D. and M. Arstall and C. Zeitz",

note = "Dreyer, Rachel P Beltrame, John F Neil, Christopher Air, Tracy Tavella, Rosanna Hoffmann, Bernadette Pati, Purendra K Di Fiore, David Arstall, Margaret Zeitz, Christopher eng Comparative Study Am J Cardiol. 2013 Jul 15;112(2):143-9. doi: 10.1016/j.amjcard.2013.03.007. Epub 2013 Apr 27.",

year = "2013",

doi = "10.1016/j.amjcard.2013.03.007",

language = "English",

volume = "112",

pages = "143--149",

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AU - Dreyer, R. P.

AU - Beltrame, J. F.

AU - Neil, C.

AU - Air, T.

AU - Tavella, R.

AU - Hoffmann, B.

AU - Pati, P. K.

AU - Di Fiore, D.

AU - Arstall, M.

AU - Zeitz, C.

N1 - Dreyer, Rachel P Beltrame, John F Neil, Christopher Air, Tracy Tavella, Rosanna Hoffmann, Bernadette Pati, Purendra K Di Fiore, David Arstall, Margaret Zeitz, Christopher eng Comparative Study Am J Cardiol. 2013 Jul 15;112(2):143-9. doi: 10.1016/j.amjcard.2013.03.007. Epub 2013 Apr 27.

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AB - Several biologic and clinical factors contribute to the increased 30-day mortality and re-infarction rate in women with ST-segment elevation myocardial infarction (STEMI). Sex differences in cardiac hemodynamic parameters such as pulmonary capillary wedge pressure (PCWP) have not been examined and might play an important role. The objectives of the present study were to examine whether female sex is an independent determinant of PCWP during acute STEMI and whether an elevated PCWP contributes to all-cause 30-day mortality and re-infarction in women. The clinical, angiographic, and hemodynamic features of 470 consecutive patients with STEMI (n = 135 women) undergoing emergency coronary angiography with right-side heart catheterization were evaluated with respect to sex. Women had an elevated PCWP (20 +/- 8 vs 16 +/- 7 mm Hg, p

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