Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences

Akila Rekima; Lieke van den Elsen; Charlotte Isnard; Danielle J. Smyth; Miriam A. Lynn; Tee Yee; Natalie E. Stevens; Savannah Machado; Nivedithaa Divakara; Maheshwar Bhasin; M. Christian Tjiam; Candia Rowel; Florence Servant; Remy Burcelin; Richard Locksley; Rick Maizels; David J. Lynn; Thomas Egwang; Valérie Verhasselt

doi:10.1111/all.16054

Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences

Akila Rekima, Lieke van den Elsen, Charlotte Isnard, Danielle J. Smyth, Miriam A. Lynn, Tee Yee, Natalie E. Stevens, Savannah Machado, Nivedithaa Divakara, Maheshwar Bhasin, M. Christian Tjiam, Candia Rowel, Florence Servant, Remy Burcelin, Richard Locksley, Rick Maizels, David J. Lynn, Thomas Egwang, Valérie Verhasselt

Lynn Systems Immunology Group

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Original language	English
Journal	Allergy: European Journal of Allergy and Clinical Immunology
DOIs	https://doi.org/10.1111/all.16054
Publication status	Accepted/In press - 2024

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1111/all.16054

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Rekima, A., van den Elsen, L., Isnard, C., Smyth, D. J., Lynn, M. A., Yee, T., Stevens, N. E., Machado, S., Divakara, N., Bhasin, M., Tjiam, M. C., Rowel, C., Servant, F., Burcelin, R., Locksley, R., Maizels, R., Lynn, D. J., Egwang, T., & Verhasselt, V. (Accepted/In press). Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences. Allergy: European Journal of Allergy and Clinical Immunology. https://doi.org/10.1111/all.16054

@article{19df67b173c048169d27e983d342fc3f,

title = "Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences",

author = "Akila Rekima and {van den Elsen}, Lieke and Charlotte Isnard and Smyth, {Danielle J.} and Lynn, {Miriam A.} and Tee Yee and Stevens, {Natalie E.} and Savannah Machado and Nivedithaa Divakara and Maheshwar Bhasin and Tjiam, {M. Christian} and Candia Rowel and Florence Servant and Remy Burcelin and Richard Locksley and Rick Maizels and Lynn, {David J.} and Thomas Egwang and Val{\'e}rie Verhasselt",

note = "Funding Information: The authors would like to thank Simone Ross and Caitlin Murray at the Harry Perkins Institute for Medical Research, the Gnotobiotic facilities and the technical assistance of staff in the South Australian Health and Medical Research Institute (SAHMRI) Preclinical Imaging and Research Laboratories (PIRL) and Translational Research Institute (TRI). Flow cytometry analysis was performed with the help of Catherine Rinaldi from the Cytometry Centre of Microscopy Characterisation, and Analysis (CMCA, UWA) and at the ACRF Cellular Imaging and Cytometry Core Facility in SAHMRI. The ACRF Facility is generously supported by the Detmold Hoopman Group, Australian Cancer Research Foundation and Australian Government through the Zero Childhood Cancer Program. We also thank Benjamin Lelouvier from Vaiomer for the data analysis. VV, LE, AR, SM, MB and ND were supported by the Larsson‐Rosenquist Foundation. AR and LE were supported by a Raine collaborative grant award. DJL was supported by an EMBL Australia Group Leader award. RMM thanks the Wellcome Trust for support through an Investigator Award (Ref 219530), and core‐funded Wellcome Centre for Integrative Parasitology (Ref: 104111). ",

year = "2024",

doi = "10.1111/all.16054",

language = "English",

journal = "Allergy: European Journal of Allergy and Clinical Immunology",

issn = "0105-4538",

publisher = "Wiley-Blackwell",

}

Rekima, A, van den Elsen, L, Isnard, C, Smyth, DJ, Lynn, MA, Yee, T, Stevens, NE, Machado, S, Divakara, N, Bhasin, M, Tjiam, MC, Rowel, C, Servant, F, Burcelin, R, Locksley, R, Maizels, R, Lynn, DJ, Egwang, T & Verhasselt, V 2024, 'Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences', Allergy: European Journal of Allergy and Clinical Immunology. https://doi.org/10.1111/all.16054

TY - JOUR

T1 - Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences

AU - Rekima, Akila

AU - van den Elsen, Lieke

AU - Isnard, Charlotte

AU - Smyth, Danielle J.

AU - Lynn, Miriam A.

AU - Yee, Tee

AU - Stevens, Natalie E.

AU - Machado, Savannah

AU - Divakara, Nivedithaa

AU - Bhasin, Maheshwar

AU - Tjiam, M. Christian

AU - Rowel, Candia

AU - Servant, Florence

AU - Burcelin, Remy

AU - Locksley, Richard

AU - Maizels, Rick

AU - Lynn, David J.

AU - Egwang, Thomas

AU - Verhasselt, Valérie

N1 - Funding Information: The authors would like to thank Simone Ross and Caitlin Murray at the Harry Perkins Institute for Medical Research, the Gnotobiotic facilities and the technical assistance of staff in the South Australian Health and Medical Research Institute (SAHMRI) Preclinical Imaging and Research Laboratories (PIRL) and Translational Research Institute (TRI). Flow cytometry analysis was performed with the help of Catherine Rinaldi from the Cytometry Centre of Microscopy Characterisation, and Analysis (CMCA, UWA) and at the ACRF Cellular Imaging and Cytometry Core Facility in SAHMRI. The ACRF Facility is generously supported by the Detmold Hoopman Group, Australian Cancer Research Foundation and Australian Government through the Zero Childhood Cancer Program. We also thank Benjamin Lelouvier from Vaiomer for the data analysis. VV, LE, AR, SM, MB and ND were supported by the Larsson‐Rosenquist Foundation. AR and LE were supported by a Raine collaborative grant award. DJL was supported by an EMBL Australia Group Leader award. RMM thanks the Wellcome Trust for support through an Investigator Award (Ref 219530), and core‐funded Wellcome Centre for Integrative Parasitology (Ref: 104111).

PY - 2024

Y1 - 2024

UR - http://www.scopus.com/inward/record.url?scp=85185450022&partnerID=8YFLogxK

U2 - 10.1111/all.16054

DO - 10.1111/all.16054

M3 - Letter

C2 - 38348877

AN - SCOPUS:85185450022

SN - 0105-4538

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

ER -

Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences

ASJC Scopus subject areas

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