TY - JOUR
T1 - Determinants of male reproductive health disorders
T2 - The men in Australia telephone survey (MATeS)
AU - Holden, Carol A.
AU - McLachlan, Robert I.
AU - Pitts, Marian
AU - Cumming, Robert
AU - Wittert, Gary
AU - Ehsani, Johnathon P.
AU - De Kretser, David M.
AU - Handelsman, David J.
N1 - Funding Information:
The financial support of the Andrology Australia program by the Australian Government Department of Health and Ageing is acknowledged by the authors. The authors also wish to acknowledge the assistance of the Hunter Valley Research Foundation, NSW in survey administration, data collection and statistical data analysis. Statistical analysis and advice from Mr Paul Agius (Australian Research Centre in Sex, Health and Society, La Trobe University, Vic) and A/Prof Damien Jolley (Monash Institute of Health Services Research, Vic) is also gratefully acknowledged together with the constructive criticism of this manuscript by Dr Megan Cock. The authors thank Dr Veronica Collins (Andrology Australia) for help with editing the manuscript. The Centre for Clinical Effectiveness, Monash Institute of Health Services Research is also acknowledged for their assistance in the identification of population-based studies and validated tools for the survey instrument. Finally, the authors wish to thank the men who participated in the MATeS study. Role of the Sponsor The Australian Government Department of Health and Ageing had no role in the design and conduct of the study, in the collection, analysis, interpretation of the data, or in the preparation, review or approval of the manuscript.
PY - 2010
Y1 - 2010
N2 - Background. The relationship between reproductive health disorders and lifestyle factors in middle-aged and older men is not clear. The aim of this study is to describe lifestyle and biomedical associations as possible causes of erectile dysfunction (ED), prostate disease (PD), lower urinary tract symptoms (LUTS) and perceived symptoms of androgen deficiency (pAD) in a representative population of middle-aged and older men, using the Men in Australia Telephone Survey (MATeS). Methods. A representative sample (n = 5990) of men aged 40+ years, stratified by age and State, was contacted by random selection of households, with an individual response rate of 78%. All men participated in a 20-minute computer-assisted telephone interview exploring general and reproductive health. Associations between male reproductive health disorders and lifestyle and biomedical factors were analysed using multivariate logistic regression (odds ratio [95% confidence interval]). Variables studied included age, body mass index, waist circumference, smoking, alcohol consumption, physical activity, co-morbid disease and medication use for hypertension, high cholesterol and symptoms of depression. Results. Controlling for age and a range of lifestyle and co-morbid exposures, sedentary lifestyle and being underweight was associated with an increased likelihood of ED (1.4 [1.1-1.8]; 2.9 [1.5-5.8], respectively) and pAD (1.3 [1.1-1.7]; 2.7 [1.4-5.0], respectively. Diabetes and cardiovascular disease were both associated with ED, with hypertension strongly associated with LUTS and pAD. Current smoking (inverse association) and depressive symptomatology were the only variables independently associated with PD. All reproductive disorders showed consistent associations with depression (measured either by depressive symptomatology or medication use) in both age-adjusted and multivariate analyses. Conclusion. A range of lifestyle factors, more often associated with chronic disease, were significantly associated with male reproductive health disorders. Education strategies directed to improving general health may also confer benefits to male reproductive health.
AB - Background. The relationship between reproductive health disorders and lifestyle factors in middle-aged and older men is not clear. The aim of this study is to describe lifestyle and biomedical associations as possible causes of erectile dysfunction (ED), prostate disease (PD), lower urinary tract symptoms (LUTS) and perceived symptoms of androgen deficiency (pAD) in a representative population of middle-aged and older men, using the Men in Australia Telephone Survey (MATeS). Methods. A representative sample (n = 5990) of men aged 40+ years, stratified by age and State, was contacted by random selection of households, with an individual response rate of 78%. All men participated in a 20-minute computer-assisted telephone interview exploring general and reproductive health. Associations between male reproductive health disorders and lifestyle and biomedical factors were analysed using multivariate logistic regression (odds ratio [95% confidence interval]). Variables studied included age, body mass index, waist circumference, smoking, alcohol consumption, physical activity, co-morbid disease and medication use for hypertension, high cholesterol and symptoms of depression. Results. Controlling for age and a range of lifestyle and co-morbid exposures, sedentary lifestyle and being underweight was associated with an increased likelihood of ED (1.4 [1.1-1.8]; 2.9 [1.5-5.8], respectively) and pAD (1.3 [1.1-1.7]; 2.7 [1.4-5.0], respectively. Diabetes and cardiovascular disease were both associated with ED, with hypertension strongly associated with LUTS and pAD. Current smoking (inverse association) and depressive symptomatology were the only variables independently associated with PD. All reproductive disorders showed consistent associations with depression (measured either by depressive symptomatology or medication use) in both age-adjusted and multivariate analyses. Conclusion. A range of lifestyle factors, more often associated with chronic disease, were significantly associated with male reproductive health disorders. Education strategies directed to improving general health may also confer benefits to male reproductive health.
UR - http://www.scopus.com/inward/record.url?scp=77949684468&partnerID=8YFLogxK
U2 - 10.1186/1471-2458-10-96
DO - 10.1186/1471-2458-10-96
M3 - Article
C2 - 20181284
AN - SCOPUS:77949684468
SN - 1471-2458
VL - 10
JO - BMC public health
JF - BMC public health
M1 - 96
ER -