Mice were fed a chow diet plus 10% cellulose, 10% fish oil or 10% sunflower oil for 3 weeks, then exposed to 100% oxygen for 75 h. Large changes in lung fatty acid composition occurred, but this did not affect hyperoxic lung damage nor levels of thiobarbituric acid reactive substances or myeloperoxidase in lungs of mice following exposure to hyperoxia. Thus there is no evidence that the ingestion of large quantities of fish oil increased the susceptibility to the oxidative stress induced by hyperoxia.
|Number of pages||4|
|Journal||Prostaglandins, Leukotrienes and Essential Fatty Acids|
|Publication status||Published or Issued - Dec 1993|
ASJC Scopus subject areas
- Clinical Biochemistry
- Cell Biology