Effects of a fish oil rich diet on hyperoxic lung damage in mice

D. Jamieson, Y. Lin, R. Gibson

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Mice were fed a chow diet plus 10% cellulose, 10% fish oil or 10% sunflower oil for 3 weeks, then exposed to 100% oxygen for 75 h. Large changes in lung fatty acid composition occurred, but this did not affect hyperoxic lung damage nor levels of thiobarbituric acid reactive substances or myeloperoxidase in lungs of mice following exposure to hyperoxia. Thus there is no evidence that the ingestion of large quantities of fish oil increased the susceptibility to the oxidative stress induced by hyperoxia.

Original languageEnglish
Pages (from-to)969-972
Number of pages4
JournalProstaglandins, Leukotrienes and Essential Fatty Acids
Issue number6
Publication statusPublished or Issued - Dec 1993

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology

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