End Rheumatic Heart Disease Centre of Research Excellence. Impact Report 2014 - 2021. Creating the blueprint to eliminate rheumatic heart disease in Australia

Jonathan R. Carapetis, Graeme McGuire, Bart J. Currie, Dawn Bessarab, Daniel McAullay, Heather D'Antoine, Alex Brown, Anna P. Ralph, Andrew Steer, Nick de Klerk

Research output: Book/ReportOther report


The END RHD Centre of Research Excellence was designed as a research-policy-service partnership
to develop the first evidence-based strategy to end rheumatic heart disease in Australia, bringing the prevalence of rheumatic heart disease for Aboriginal and Torres Strait Islander peoples down to the same level as non-Indigenous people in Australians.
When the END RHD CRE was funded in 2014, RHD control was at a critical juncture in Australia. More than 20 years of research closely linked to service delivery and policymaking had placed Australia at the forefront of global ARF and RHD research, control and advocacy, however a surge of co-ordinated research and implementation strategies was needed to accelerate progress. The END RHD CRE provided an opportunity for a strategic approach targeting implementation science, encompassing all domains of disease control, consolidating existing strategies, developing new interventions with potential for rapid benefits, and modelling the effect of potential interventions.
The production of the Endgame Strategy involved the synthesis of information across the five-year lifespan of the END RHD CRE. Funding was allocated to priority research projects across several disciplines of research, including epidemiology, economics, biomedical sciences, clinical practice, health services research and social sciences, with a dedicated focus on engaging the RHD community and documenting the experiences of those living with the disease. Data and results from these priority projects helped inform the overall Endgame Strategy and were complemented by literature reviews, systematic reviews, narrative reviews and the experiences of health professionals currently working in ARF and RHD control.
Original languageEnglish
Number of pages28
Publication statusPublished or Issued - May 2021


  • rheumatic heart disease

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