Fibre-optic photochemical stroke: Generating and measuring photochemical changes inside the brain

G. Tsiminis, T. S. Klarić, E. P. Schartner, S. C. Warren-Smith, M. D. Lewis, S. A. Koblar, T. M. Monro

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

We report here on the development of a method to induce a stroke in a specific location within a mouse brain through the use of an optical fibre. By capturing the emitted fluorescence signal generated using the same fibre it is then possible to monitor photochemical changes within the brain in real-time, potentially reducing the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal.

Original languageEnglish
Title of host publication23rd International Conference on Optical Fibre Sensors
PublisherSPIE
ISBN (Print)9781628411751
DOIs
Publication statusPublished or Issued - 2014
Externally publishedYes
Event23rd International Conference on Optical Fibre Sensors - Santander, Spain
Duration: 2 Jun 20146 Jun 2014

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9157
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

Other23rd International Conference on Optical Fibre Sensors
Country/TerritorySpain
CitySantander
Period2/06/146/06/14

Keywords

  • Fluorescence detection
  • In-vivo sensor
  • Optical fibre sensor
  • Photochemical stroke

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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