Fixed or Rotating Night Shift Work Undertaken by Women: Implications for Fertility and Miscarriage

Renae C. Fernandez, Jennifer L. Marino, Tamara J. Varcoe, Scott Davis, Lisa J. Moran, Alice R. Rumbold, Hannah M. Brown, Melissa J. Whitrow, Michael J. Davies, Vivienne M. Moore

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)


This review summarizes the evidence concerning effects of night shift work on women's reproductive health, specifically difficulty in conceiving and miscarriage. We distinguish between fixed night shift and rotating night shift, as the population subgroups exposed, the social and biological mechanisms, and the magnitude of effects are likely to differ; of note, women working fixed night shift are known to have high tolerance for this schedule. We identified two relevant systematic reviews with meta-analyses and five additional studies. Night shift work may give rise to menstrual cycle disturbances, but effect sizes are imprecise. Endometriosis may be elevated in night shift workers, but evidence is only preliminary. Adequate data are lacking to assess associations between night shift work and infertility or time to pregnancy. The weight of evidence begins to point to working at night, whether in fixed or rotating shifts, as a risk factor for miscarriage. There are many methodological problems with this literature, with substantial variation in the definitions of night shift and schedule types making comparisons between studies difficult and pooling across studies questionable. Nevertheless, there appears to be grounds for caution and counselling where women have concerns about night shift work and their reproductive health.

Original languageEnglish
Pages (from-to)74-82
Number of pages9
JournalSeminars in Reproductive Medicine
Issue number2
Publication statusPublished or Issued - 8 Feb 2016
Externally publishedYes


  • fertility
  • miscarriage
  • night shift work
  • pregnancy
  • shift work

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Obstetrics and Gynaecology
  • Physiology (medical)

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