Fluid Therapy: Friend or Foe?

Erin Grace, Amy K. Keir

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


Many questions surround fluid bolus therapy and subsequent fluid management in neonatal critical care as they do in pediatric and adult critical care. This review explores the known key clinical aspects of fluid bolus therapy and fluid balance in the first 7 days of life and provides suggestions for further work in this area. It draws on the pediatric and adult critical care literature to provide thought-provoking data around the potential harms of excessive intravenous fluids, which may prove relevant to neonatology. Current data suggest that fluid bolus therapy and early-life positive fluid balance in neonates may be associated with harm.

Original languageEnglish
Pages (from-to)515-528
Number of pages14
JournalClinics in Perinatology
Issue number3
Publication statusPublished or Issued - Sept 2020


  • Fluid therapy/methods
  • Infant
  • Newborn

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

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