Abstract
The gastrointestinal (GI) tract has a multitude of roles including ingestion; digestion of food; absorption of nutrients and water; elimination of waste; and defense against toxins, antigens, and pathogens. To meet these challenges, there is an elaborate sensory system, with distinct chemo- and mechanosensory modalities, that monitors the various processes along the GI tract, providing feedback and maintaining physiological function. This chapter will focus on physiological and pathophysiological mechanosensory processes within the wall of the gut and along the whole length of the GI tract.
Original language | English |
---|---|
Title of host publication | Mechanobiology in Health and Disease |
Publisher | Elsevier |
Pages | 377-414 |
Number of pages | 38 |
ISBN (Electronic) | 9780128129524 |
ISBN (Print) | 9780128129531 |
DOIs | |
Publication status | Published or Issued - 1 Jan 2018 |
Keywords
- Enteric nervous system
- Enterochromaffin cells
- Gastrointestinal tract
- Interstitial cells of cajal
- Mechanosensation
- Obesity
- Pain
- Smooth muscle cells
- Spinal afferents
- Vagal afferents
ASJC Scopus subject areas
- General Engineering
- General Biochemistry,Genetics and Molecular Biology