Herpes Simplex Virus induces Fos expression in rat brainstem neurons

Z. J. Gieroba; B. S. Zhu; W. W. Blessing; S. L. Wesselingh

doi:10.1016/0006-8993(95)00016-J

Herpes Simplex Virus induces Fos expression in rat brainstem neurons

Z. J. Gieroba
, B. S. Zhu
, W. W. Blessing
, S. L. Wesselingh

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.

Original language	English
Pages (from-to)	329-332
Number of pages	4
Journal	Brain Research
Volume	675
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(95)00016-J
Publication status	Published or Issued - 27 Mar 1995
Externally published	Yes

Keywords

Fos
Herpes simplex virus
Medulla oblongata
Vagus nerve

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

Access to Document

10.1016/0006-8993(95)00016-J

Cite this

@article{f9638d0ea55e41fd9f6425cd5c72608f,

title = "Herpes Simplex Virus induces Fos expression in rat brainstem neurons",

abstract = "After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.",

keywords = "Fos, Herpes simplex virus, Medulla oblongata, Vagus nerve",

author = "Gieroba, \{Z. J.\} and Zhu, \{B. S.\} and Blessing, \{W. W.\} and Wesselingh, \{S. L.\}",

year = "1995",

month = mar,

day = "27",

doi = "10.1016/0006-8993(95)00016-J",

language = "English",

volume = "675",

pages = "329--332",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier B.V.",

number = "1-2",

}

TY - JOUR

T1 - Herpes Simplex Virus induces Fos expression in rat brainstem neurons

AU - Gieroba, Z. J.

AU - Zhu, B. S.

AU - Blessing, W. W.

AU - Wesselingh, S. L.

PY - 1995/3/27

Y1 - 1995/3/27

N2 - After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.

AB - After the injection of Herpes Simplex Virus type 1 into the rat cervical vagus nerve, transneuronally labelled virus-containing neurons and glial cells were present in the medulla oblongata. Fos-containing nuclei were present in the same regions of the brain. A double-labelling procedure revealed that most of the virus-positive neurons also contained Fos-positive nuclei. Appearance of HSV1 antigen within the CNS is associated with Fos expression in neurons and glial cells.

KW - Fos

KW - Herpes simplex virus

KW - Medulla oblongata

KW - Vagus nerve

UR - https://www.scopus.com/pages/publications/0028986569

U2 - 10.1016/0006-8993(95)00016-J

DO - 10.1016/0006-8993(95)00016-J

M3 - Article

C2 - 7796147

AN - SCOPUS:0028986569

SN - 0006-8993

VL - 675

SP - 329

EP - 332

JO - Brain Research

JF - Brain Research

IS - 1-2

ER -

Herpes Simplex Virus induces Fos expression in rat brainstem neurons

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this