Abstract
Twin girls presented with infantile cortical periostosis (Caffey's disease) at 2 and 3 weeks of age, respectively. This disorder initially involved their upper and lower limbs and resulted in fever, irritability and tenderness. X-rays showed extensive periosteal new bone formation. Multiple relapses occurred in the first year of life and during some of these relapses mandibular and clavicular involvement was noted. Prednisolone, 1 mg/kg per day, was used to treat relapses until 9 months of age. Indomethacin therapy at this age at a dose of 3 mg/kg per day allowed the cessation of prednisolone therapy and disease flares were thereafter infrequent and responsive to indomethacin.
Original language | English |
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Pages (from-to) | 305-308 |
Number of pages | 4 |
Journal | Journal of Paediatrics and Child Health |
Volume | 37 |
Issue number | 3 |
DOIs | |
Publication status | Published or Issued - 2001 |
Keywords
- Bone
- Caffey's disease
- Indomethacin
- Infantile cortical periostosis
- Prostaglandin synthetase inhibitors
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health