Molecular Bases of Pathological Growth

Jesus Argente, Luis A. Perez-Jurado, Juan F. Sotos, Jesus Argente

Research output: Contribution to journalArticlepeer-review


Due to the tremendous advances in molecular biology techniques in recent years, our knowledge of the genetic basis of pathological human growth has expanded dramatically. Pathological growth includes both overgrowth and undergrowth, with undergrowth being generally classified into either proportionate or disproportionate growth. Each of these classifications of pathological human growth can now be associated with specific gene alterations. Here we review the different genes, and their various alterations, that are currently known to be implicated in these processes.

Original languageEnglish
Pages (from-to)179-210
Number of pages32
JournalInternational Journal on Disability and Human Development
Issue number4
Publication statusPublished or Issued - 2000
Externally publishedYes


  • genes
  • overgrowth
  • short stature
  • skeletal dysplasias

ASJC Scopus subject areas

  • Rehabilitation
  • Sensory Systems
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Advanced and Specialised Nursing
  • Speech and Hearing

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