TY - JOUR
T1 - Obesity and periodontal outcomes
T2 - A population-based cohort study in Brazil
AU - Nascimento, Gustavo G.
AU - Peres, Karen G.
AU - Mittinty, Murthy N.
AU - Mejia, Gloria C.
AU - Silva, Diego A.
AU - Gonzalez-Chica, David
AU - Peres, Marco A.
N1 - Publisher Copyright:
© 2017, American Academy of Periodontology. All rights reserved.
PY - 2017/1
Y1 - 2017/1
N2 - Background: The aim of this study is to investigate the effects of abdominal and general obesity on periodontal outcomes in a population-based cohort of Brazilian adults. Methods: Abdominal and general obesity were assessed in the years 2009 (n = 1,720) and 2012 (n = 1,222). For abdominal obesity, a dichotomous variable was created: 1) eutrophic/lost weight or 2) obese/gained weight. For general obesity, a categorical variable was created: 1) eutrophic/lost weight; 2) gained weight; or 3) obese. Periodontal outcomes were percentage of teeth with bleeding on probing (BOP) and combination of BOP and attachment loss (AL). Hypertension was set as the mediator. Marginal structural models (MSMs) were used to estimate the controlled direct effect of obesity on periodontal outcomes. Results: Periodontal data were presented from 1,066 participants. The total effect model showed those with general obesity in the cohort period presented higher risk of unfavorable periodontal outcomes (rate ratio [RR]: 1.45 for AL and BOP in different teeth; RR: 1.84 for AL and BOP in the same tooth). Estimates from MSMs revealed an effect of general obesity on AL and BOP in different teeth (RR: 1.44). No effect of general obesity was noted on the percentage of BOP. Total effect of abdominal obesity increased risk of AL and BOP in different teeth (RR: 1.47), AL and BOP in the same tooth (RR: 2.77), and percentage of BOP (RR: 1.49). In a MSM, those with abdominal obesity presented greater risk of AL and BOP in the same tooth (RR: 2.16) and percentage of BOP (RR: 1.37). Conclusion: Abdominal obesity has a direct effect on unfavorable periodontal outcomes in MSMs.
AB - Background: The aim of this study is to investigate the effects of abdominal and general obesity on periodontal outcomes in a population-based cohort of Brazilian adults. Methods: Abdominal and general obesity were assessed in the years 2009 (n = 1,720) and 2012 (n = 1,222). For abdominal obesity, a dichotomous variable was created: 1) eutrophic/lost weight or 2) obese/gained weight. For general obesity, a categorical variable was created: 1) eutrophic/lost weight; 2) gained weight; or 3) obese. Periodontal outcomes were percentage of teeth with bleeding on probing (BOP) and combination of BOP and attachment loss (AL). Hypertension was set as the mediator. Marginal structural models (MSMs) were used to estimate the controlled direct effect of obesity on periodontal outcomes. Results: Periodontal data were presented from 1,066 participants. The total effect model showed those with general obesity in the cohort period presented higher risk of unfavorable periodontal outcomes (rate ratio [RR]: 1.45 for AL and BOP in different teeth; RR: 1.84 for AL and BOP in the same tooth). Estimates from MSMs revealed an effect of general obesity on AL and BOP in different teeth (RR: 1.44). No effect of general obesity was noted on the percentage of BOP. Total effect of abdominal obesity increased risk of AL and BOP in different teeth (RR: 1.47), AL and BOP in the same tooth (RR: 2.77), and percentage of BOP (RR: 1.49). In a MSM, those with abdominal obesity presented greater risk of AL and BOP in the same tooth (RR: 2.16) and percentage of BOP (RR: 1.37). Conclusion: Abdominal obesity has a direct effect on unfavorable periodontal outcomes in MSMs.
KW - Causality
KW - Epidemiologic methods
KW - Longitudinal studies
KW - Nutritional status
KW - Periodontitis
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=85007275614&partnerID=8YFLogxK
U2 - 10.1902/jop.2016.160361
DO - 10.1902/jop.2016.160361
M3 - Article
C2 - 27611339
AN - SCOPUS:85007275614
SN - 0022-3492
VL - 88
SP - 50
EP - 58
JO - Journal of Periodontology
JF - Journal of Periodontology
IS - 1
ER -