One-pot Suzuki-Heck relay to prepare industrially valuable intermediates using the Pd-Cy∗Phine catalyst system

Uttam K. Das, Roxanne Clément, Charles W. Johannes, Edward G. Robins, Howard Jong, R. Tom Baker

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


A rare example of a one-pot, palladium-catalyzed Suzuki-Heck sequence has been developed with applicability to APIs and organoelectronic materials. High throughput screening was used to expedite development and survey strategies. Interchangeability of the coupling partners and the avoidance of intermediate isolation gives operational flexibility, which can be used to improve process efficiency and suppress by-product formation.

Original languageEnglish
Pages (from-to)4599-4603
Number of pages5
JournalCatalysis Science and Technology
Issue number20
Publication statusPublished or Issued - 2017
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis

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