Optimization of whispering gallery mode sensor design for applications in biosensing

T. Reynolds, A. François, M. R. Henderson, S. J. Nicholls, T. M. Monro

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Whispering gallery modes (WGM) within microsphere cavities have demonstrated the ability to provide label-free, highly sensitive and selective detection down to a single molecule level, emerging as a promising technology for future biosensing applications. Currently however, the majority of biosensing work utilizing WGMs has been conducted in resonators made from either silica or polystyrene while other materials have been largely uninvestigated. This work looks to predict the optimal combinations of material, resonator size and excitation/coupling scheme to provide guidelines to assist in decision making when undertaking refractive index biosensing in a range of situations.

Original languageEnglish
Title of host publicationDesign and Quality for Biomedical Technologies VIII
EditorsRongguang Liang, Ramesh Raghavachari
ISBN (Electronic)9781628414059
Publication statusPublished or Issued - 2015
EventDesign and Quality for Biomedical Technologies VIII - San Francisco, United States
Duration: 7 Feb 20158 Feb 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherDesign and Quality for Biomedical Technologies VIII
Country/TerritoryUnited States
CitySan Francisco


  • Biosensing
  • Microsphere
  • Optimization
  • Whispering gallery modes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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