Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases

Terry Boyle; Joseph M. Connors; Randy D. Gascoyne; Brian R. Berry; Laurie H. Sehn; Morteza Bashash; John J. Spinelli

doi:10.1111/bjh.14702

Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases

Terry Boyle, Joseph M. Connors, Randy D. Gascoyne, Brian R. Berry, Laurie H. Sehn, Morteza Bashash, John J. Spinelli

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0·59, 95% confidence interval (CI) = 0·36–0·96], while obese follicular lymphoma cases had a 2·5-fold risk of dying (HR = 2·52, 95% CI = 1·27–5·00) compared with cases with normal BMI. NHL-specific survival results were similar.

Original language	English
Pages (from-to)	442-447
Number of pages	6
Journal	British Journal of Haematology
Volume	178
Issue number	3
DOIs	https://doi.org/10.1111/bjh.14702
Publication status	Published or Issued - Aug 2017
Externally published	Yes

Keywords

body mass index
diffuse large B-cell lymphoma
follicular lymphoma
physical activity
prognosis

ASJC Scopus subject areas

Hematology

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10.1111/bjh.14702

Cite this

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title = "Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases",

abstract = "There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0·59, 95% confidence interval (CI) = 0·36–0·96], while obese follicular lymphoma cases had a 2·5-fold risk of dying (HR = 2·52, 95% CI = 1·27–5·00) compared with cases with normal BMI. NHL-specific survival results were similar.",

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AU - Boyle, Terry

AU - Connors, Joseph M.

AU - Gascoyne, Randy D.

AU - Berry, Brian R.

AU - Sehn, Laurie H.

AU - Bashash, Morteza

AU - Spinelli, John J.

PY - 2017/8

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AB - There is limited information concerning the impact of physical activity and obesity on non-Hodgkin lymphoma (NHL) prognosis. We examined the associations between pre-diagnosis physical activity and body mass index (BMI) with survival in 238 diffuse large B-cell (DLBCL) and 175 follicular lymphoma cases, with follow-up from 2000 to 2015. The most physically active DLBCL cases had 41% lower risk of dying in the follow-up period than the least active [Hazard ratio (HR) = 0·59, 95% confidence interval (CI) = 0·36–0·96], while obese follicular lymphoma cases had a 2·5-fold risk of dying (HR = 2·52, 95% CI = 1·27–5·00) compared with cases with normal BMI. NHL-specific survival results were similar.

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Physical activity, obesity and survival in diffuse large B-cell and follicular lymphoma cases

Abstract

Keywords

ASJC Scopus subject areas

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