Postural tachycardia syndrome: Current perspectives

Rachel Wells, Andrew J. Spurrier, Dominik Linz, Celine Gallagher, Rajiv Mahajan, Prash Sanders, Amanda Page, Dennis H. Lau

Research output: Contribution to journalReview articlepeer-review

27 Citations (Scopus)


Postural tachycardia syndrome (POTS) is the combination of an exaggerated heart rate response to standing, in association with symptoms of lightheadedness or pre-syncope that improve when recumbent. The condition is often associated with fatigue and brain fog, resulting in significant disruptions at a critical time of diagnosis in adolescence and young adulthood. The heterogeneity of the underlying pathophysiology and the variable response to therapeutic interventions make management of this condition challenging for both patients and physicians alike. Here, we aim to review the factors and mechanisms that may contribute to the symptoms and signs of POTS and to present our perspectives on the clinical approach toward the diagnosis and management of this complex syndrome.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalVascular Health and Risk Management
Publication statusPublished or Issued - 29 Dec 2018


  • Autonomic
  • Baroreflex
  • Doppler
  • Hypermobility
  • Orthostatic

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Hematology
  • Public Health, Environmental and Occupational Health
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

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