Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: A national, population-based study

Robin M. Daly, Claudia Gagnon, Zhong X. Lu, Dianna J. Magliano, David W. Dunstan, Ken A. Sikaris, Paul Z. Zimmet, Peter R. Ebeling, Jonathan E. Shaw

Research output: Contribution to journalArticlepeer-review

243 Citations (Scopus)


Objective: Vitamin D deficiency is recognized as a global public health problem, but the population-based prevalence of deficiency and its determinants in Australian adults is not known. This study evaluated the vitamin D status of Australian adults aged ≥25 years and risk factors associated with vitamin D deficiency in this population. Design and Patients: We studied a national sample of 11 247 Australian adults enrolled in the 1999/2000 Australian Diabetes, Obesity and Lifestyle (AusDiab) study drawn from 42 randomly selected districts throughout Australia. Measurements: Serum concentrations of 25-hydroxyvitamin D [25(OH)D] were measured by immunoassay. Vitamin D deficiency was defined as a concentration <50 nmol/l. Information on demographic and lifestyle factors was derived from interview-administered questionnaires. Results: The mean serum 25(OH)D concentration was 63 nmol/l (95% CI: 59-67 nmol/l). Only 4% of the population had a level <25 nmol/l, but the prevalence of vitamin D deficiency (<50 nmol/l) was 31% (22% men; 39% women); 73% had levels <75 nmol/l. The prevalence of vitamin D deficiency increased significantly with age, was greater in women, in those of non-Europid origin, in the obese and those who were physically inactive and with a higher level of education. Deficiency was also more common during winter and in people residing in southern Australia (latitude >35°S); 42% of women and 27% of men were deficient during summer- autumn, which increased to 58% and 35%, respectively, during winter-spring. Conclusion: Vitamin D deficiency is common in Australia affecting nearly one-third of adults aged ≥25 years. This indicates that strategies are needed at the population level to improve vitamin D status of Australians.

Original languageEnglish
Pages (from-to)26-35
Number of pages10
JournalClinical Endocrinology
Issue number1
Publication statusPublished or Issued - Jul 2012

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this