Review: Exploring coronary atherosclerosis with intravascular imaging

Rishi Puri, E. Murat Tuzcu, Steven E. Nissen, Stephen J. Nicholls

Research output: Contribution to journalReview articlepeer-review

39 Citations (Scopus)


Coronary angiography has been widely used for five decades to evaluate a range of vascular pathologies and triage patients to therapeutic interventions. The inability to directly visualize the artery wall with conventional angiographic techniques has stimulated development of a number of intravascular imaging modalities. These approaches have the potential to provide a more comprehensive characterization of the burden, composition and functionality of atherosclerotic plaque, neointimal hyperplasia and allograft vasculopathy that develop within coronary arteries. The ability to use these modalities in vivo and in a serial fashion has provided a greater insight into the factors that underlie the disease process and guide therapeutic interventions.

Original languageEnglish
Pages (from-to)670-679
Number of pages10
JournalInternational Journal of Cardiology
Issue number2
Publication statusPublished or Issued - 30 Sep 2013


  • Allograft vasculopathy
  • Atherosclerosis
  • Coronary artery disease
  • Imaging
  • Neointimal hyperplasia
  • Risk factors

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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