Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?

Rajiv Mahajan; Rajeev K. Pathak; Anand Thiyagarajah; Dennis H. Lau; Francis E. Marchlinski; Sanjay Dixit; John D. Day; Jeroen M.L. Hendriks; Melinda Carrington; Jonathan M. Kalman; Prashanthan Sanders

doi:10.1016/j.hlc.2017.05.123

Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?

Rajiv Mahajan, Rajeev K. Pathak, Anand Thiyagarajah, Dennis H. Lau, Francis E. Marchlinski, Sanjay Dixit, John D. Day, Jeroen M.L. Hendriks, Melinda Carrington, Jonathan M. Kalman, Prashanthan Sanders

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.

Original language	English
Pages (from-to)	990-997
Number of pages	8
Journal	Heart Lung and Circulation
Volume	26
Issue number	9
DOIs	https://doi.org/10.1016/j.hlc.2017.05.123
Publication status	Published or Issued - Sept 2017
Externally published	Yes

Keywords

Atrial fibrillation
Atrial remodelling
Cardiovascular risk factors

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.hlc.2017.05.123

Cite this

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title = "Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?",

abstract = "Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.",

keywords = "Atrial fibrillation, Atrial remodelling, Cardiovascular risk factors",

author = "Rajiv Mahajan and Pathak, {Rajeev K.} and Anand Thiyagarajah and Lau, {Dennis H.} and Marchlinski, {Francis E.} and Sanjay Dixit and Day, {John D.} and Hendriks, {Jeroen M.L.} and Melinda Carrington and Kalman, {Jonathan M.} and Prashanthan Sanders",

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year = "2017",

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doi = "10.1016/j.hlc.2017.05.123",

language = "English",

volume = "26",

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T1 - Risk Factor Management and Atrial Fibrillation Clinics

T2 - Saving the Best for Last?

AU - Mahajan, Rajiv

AU - Pathak, Rajeev K.

AU - Thiyagarajah, Anand

AU - Lau, Dennis H.

AU - Marchlinski, Francis E.

AU - Dixit, Sanjay

AU - Day, John D.

AU - Hendriks, Jeroen M.L.

AU - Carrington, Melinda

AU - Kalman, Jonathan M.

AU - Sanders, Prashanthan

PY - 2017/9

Y1 - 2017/9

N2 - Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.

AB - Atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality worldwide. Management of AF is a complex process involving: 1) the prevention of thromboembolic complications with anticoagulation; 2) rhythm control; and 3) the detection and treatment of underlying heart disease. However, cardiometabolic risk factors, such as obesity, hypertension, diabetes mellitus, and obstructive sleep apnoea, have been proposed as contributors to the expanding epidemic of atrial fibrillation (AF). Thus, a fourth pillar of AF care would include aggressive targeting of interdependent, modifiable cardiovascular risk factors as part of an integrated care model. Such risk factor management could retard and reverse the pathological processes underlying AF and reduce AF burden.

KW - Atrial fibrillation

KW - Atrial remodelling

KW - Cardiovascular risk factors

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U2 - 10.1016/j.hlc.2017.05.123

DO - 10.1016/j.hlc.2017.05.123

M3 - Review article

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SN - 1443-9506

VL - 26

SP - 990

EP - 997

JO - Heart Lung and Circulation

JF - Heart Lung and Circulation

IS - 9

ER -

Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?

Abstract

Keywords

ASJC Scopus subject areas

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