Role of Left Ventricular Twist Mechanics in the Assessment of Cardiac Dyssynchrony in Heart Failure

Matteo Bertini, Partho P. Sengupta, Gaetano Nucifora, Victoria Delgado, Arnold C.T. Ng, Nina Ajmone Marsan, Miriam Shanks, Rutger R.J. van Bommel, Martin J. Schalij, Jagat Narula, Jeroen J. Bax

Research output: Contribution to journalReview articlepeer-review

52 Citations (Scopus)


The authors discuss an incremental value of assessing left ventricular (LV) twist mechanics in patients with heart failure (HF) and its potential usefulness in characterizing response to cardiac resynchronization therapy (CRT) and reversal of LV remodeling at 6 months follow-up. They also underscore a critical relationship between LV lead position and changes in LV twist after CRT, and suggest that the reversal of LV remodeling in HF patients following CRT primarily results from restoration of the global sequence of LV twist mechanics.

Original languageEnglish
Pages (from-to)1425-1435
Number of pages11
JournalJACC: Cardiovascular Imaging
Issue number12
Publication statusPublished or Issued - Dec 2009
Externally publishedYes


  • cardiac resynchronization therapy
  • heart failure
  • left ventricular twist

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this