Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia

T. R. Parr, R. A. Moore, L. V. Moore, R. E.W. Hancock

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Abstract

The measured outer membrane permeability of Pseudomonas cepacia to the β-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume31
Issue number1
DOIs
Publication statusPublished or Issued - 1987
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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