Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia

T. R. Parr; R. A. Moore; L. V. Moore; R. E.W. Hancock

doi:10.1128/AAC.31.1.121

Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia

T. R. Parr
, R. A. Moore
, L. V. Moore
, R. E.W. Hancock

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

The measured outer membrane permeability of Pseudomonas cepacia to the β-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.

Original language	English
Pages (from-to)	121-123
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	31
Issue number	1
DOIs	https://doi.org/10.1128/AAC.31.1.121
Publication status	Published or Issued - 1987
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.31.1.121

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title = "Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia",

abstract = "The measured outer membrane permeability of Pseudomonas cepacia to the β-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.",

author = "Parr, \{T. R.\} and Moore, \{R. A.\} and Moore, \{L. V.\} and Hancock, \{R. E.W.\}",

year = "1987",

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language = "English",

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AU - Parr, T. R.

AU - Moore, R. A.

AU - Moore, L. V.

AU - Hancock, R. E.W.

PY - 1987

Y1 - 1987

N2 - The measured outer membrane permeability of Pseudomonas cepacia to the β-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.

AB - The measured outer membrane permeability of Pseudomonas cepacia to the β-lactam nitrocefin was low: approximately 10 times less than that of Escherichia coli and comparable to that of Pseudomonas aeruginosa. The purified P. cepacia porin demonstrated an average single channel conductance in 1 M KCl of 0.23 nS.

UR - https://www.scopus.com/pages/publications/0023193236

U2 - 10.1128/AAC.31.1.121

DO - 10.1128/AAC.31.1.121

M3 - Article

C2 - 3032087

AN - SCOPUS:0023193236

SN - 0066-4804

VL - 31

SP - 121

EP - 123

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 1

ER -

Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia

Abstract

ASJC Scopus subject areas

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