Abstract
We describe the design of a randomised controlled trial to evaluate the efficacy of endometrial polyp removal in women with postmenopausal bleeding. We designed a trial in which patients with postmenopausal bleeding and endometrial thickness >4 mm undergo hysteroscopy. If during hysteroscopy an endometrial polyp was diagnosed, patients were asked to participate in this trial and after informed consent allocated to immediate removal of the polyp or expectant management. This trial suffered from lack of recruitment related both to doctors seeking for informed consent as well as to patients' unwillingness to participate in this trial. However, a randomised controlled trial on this subject is still necessary to evaluate the efficacy of uterine cavity evaluation in the diagnostic work-up of women with postmenopausal bleeding, focussing on benign pathology. Therefore, we propose an alternative design, which might be more feasible.
Original language | English |
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Pages (from-to) | 1391-1395 |
Number of pages | 5 |
Journal | BJOG: An International Journal of Obstetrics and Gynaecology |
Volume | 116 |
Issue number | 10 |
DOIs | |
Publication status | Published or Issued - Sept 2009 |
Externally published | Yes |
Keywords
- Endometrial polyps
- Postmenopausal bleeding
- Trial design
ASJC Scopus subject areas
- Obstetrics and Gynaecology