Stroke in Older Adults Living in Care Homes: Results From a National Data Linkage Study in Wales

Stephanie L. Harrison, Gregory Y.H. Lip, Ashley Akbari, Fatemeh Torabi, Leona A. Ritchie, Asangaedem Akpan, Julian Halcox, Sarah Rodgers, Joe Hollinghurst, Daniel Harris, Deirdre A. Lane

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1 Citation (Scopus)


Objectives: To determine the proportion of older people moving to care homes with a recent stroke, incidence of stroke after moving to a care home, mortality following stroke, and secondary stroke prevention management in older care home residents. Design: Retrospective cohort study using population-scale individual-level linked data sources between 2003 and 2018 in the Secure Anonymized Information Linkage (SAIL) Databank. Setting and Participants: People aged ≥65 years residing in long-term care homes in Wales. Methods: Competing risk models and logistic regression models were used to examine the association between prior stroke, incident stroke, and mortality following stroke. Results: Of 86,602 individuals, 7.0% (n = 6055) experienced a stroke in the 12 months prior to care home entry. The incidence of stroke within 12 months after entry to a care home was 26.2 per 1000 person-years [95% confidence interval (CI) 25.0, 27.5]. Previous stroke was associated with higher risk of incident stroke after moving to a care home (subdistribution hazard ratio 1.83, 95% CI 1.57, 2.13) and 30-day mortality following stroke (odds ratio 2.18, 95% CI 1.59, 2.98). Severe frailty was not significantly associated with risk of stroke or 30-day mortality following stroke. Secondary stroke prevention included statins (51.0%), antiplatelets (61.2%), anticoagulants (52.4% of those with atrial fibrillation), and antihypertensives (92.1% of those with hypertension). Conclusions and Implications: At the time of care home entry, individuals with history of stroke in the previous 12 months are at a higher risk of incident stroke and mortality following an incident stroke. These individuals are frequently not prescribed medications for secondary stroke prevention. Further evidence is needed to determine the optimal care pathways for older people living in long-term care homes with history of stroke.

Original languageEnglish
Pages (from-to)1548-1554.e11
JournalJournal of the American Medical Directors Association
Issue number9
Publication statusPublished or Issued - Sept 2022
Externally publishedYes


  • Nursing homes
  • anticoagulants
  • antiplatelets
  • cerebrovascular disease

ASJC Scopus subject areas

  • Nursing(all)
  • Health Policy
  • Geriatrics and Gerontology

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