Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies

Martalena Ramli; Ying Dong; Leonard F. Lindoy; Suzanne V. Smith; J. Gerald Wilson

doi:10.1002/jhet.5570420111

Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies

Martalena Ramli, Ying Dong, Leonard F. Lindoy, Suzanne V. Smith, J. Gerald Wilson

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The synthesis of new linked bis- and tris-ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorporating a dioxocyclam ring is also reported.

Original language	English
Pages (from-to)	77-83
Number of pages	7
Journal	Journal of Heterocyclic Chemistry
Volume	42
Issue number	1
DOIs	https://doi.org/10.1002/jhet.5570420111
Publication status	Published or Issued - 2005
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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10.1002/jhet.5570420111

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title = "Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies",

abstract = "The synthesis of new linked bis- and tris-ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorporating a dioxocyclam ring is also reported.",

author = "Martalena Ramli and Ying Dong and Lindoy, {Leonard F.} and Smith, {Suzanne V.} and Wilson, {J. Gerald}",

year = "2005",

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volume = "42",

pages = "77--83",

journal = "Journal of Heterocyclic Chemistry",

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T1 - Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies

AU - Ramli, Martalena

AU - Dong, Ying

AU - Lindoy, Leonard F.

AU - Smith, Suzanne V.

AU - Wilson, J. Gerald

PY - 2005

Y1 - 2005

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AB - The synthesis of new linked bis- and tris-ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorporating a dioxocyclam ring is also reported.

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U2 - 10.1002/jhet.5570420111

DO - 10.1002/jhet.5570420111

M3 - Article

AN - SCOPUS:17944365618

SN - 0022-152X

VL - 42

SP - 77

EP - 83

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 1

ER -

Synthesis of one-, two- and three-ring macrocyclic, bifunctional compounds for use in radiolabelling monoclonal antibodies

Abstract

ASJC Scopus subject areas

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