Systematic Evolution Of Ligands By Exponential Enrichment: Chemi-selex

Kirk Jensen (Inventor)

Research output: Patent

9 Downloads (Pure)


This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.
Original languageEnglish
Patent numberUS 6300074 B1
IPCUS 6300074 B1
Publication statusPublished or Issued - 9 Oct 2001

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