The prognostic importance of myocardial fibrosis detected by late-gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) in new-presentation dilated cardiomyopathy (DCM)

Karthigesh Sree Raman, Gaetano Nucifora, Darryl Leong, Joseph Selvanayagam, Richard J. Woodman, P. Molaee, Mitra Shirazi, Andrew D. McGavigan, Carmen G. De Pasquale

Research output: Contribution to journalArticlepeer-review

Abstract

Presence of myocardial fibrosis in DCM has been reported to be associated with increased adverse clinical outcomes. However, the presence of myocardial fibrosis at presentation in DCM, and its subsequent role in perpetuating long term left ventricular (LV) dysfunction, heart failure (HF) and ventricular arrhythmia (VA) remains unclear. Past studies did not characterise DCM patients early in their disease course, and may not have accounted for patients with significant improvement in LV function.
Original languageEnglish
JournalEuropean Heart Journal
DOIs
Publication statusPublished or Issued - 2018

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