Transforming growth factor beta in human milk does not change in response to modest intakes of docosahexaenoic acid

J. S. Hawkes, D. L. Bryan, M. A. Neumann, M. Makrides, R. A. Gibson

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Long-chain polyunsaturated fatty acids have been associated with aspects of immune regulation including cytokine production. The purpose of this study was to investigate the effect of maternal dietary supplementation with tuna oil, rich in docosahexaenoic acid (DHA), on the concentration of transforming growth factor beta 1 (TGFβ1) and TGFβ2 in breast milk. In this randomized, dietary intervention trial, mothers of term infants consumed a daily supplement of 2000 mg oil containing either placebo (n = 40), 300 mg DHA (n = 40), or 600 mg DHA (n = 40). The DHA increase in milk and plasma was proportional to dietary DHA. There was no relationship between milk DHA status and TGFβ1 and TGFβ2 levels.

Original languageEnglish
Pages (from-to)1179-1181
Number of pages3
JournalLipids
Volume36
Issue number10
DOIs
Publication statusPublished or Issued - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Cell Biology

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