TY - JOUR
T1 - Urinary incontinence in nulliparous women before and during pregnancy
T2 - Prevalence, incidence, and associated risk factors
AU - Brown, Stephanie J.
AU - Donath, Susan
AU - MacArthur, Christine
AU - McDonald, Ellie A.
AU - Krastev, Ann H.
N1 - Funding Information:
Funding This research was supported by a project grant from the Australian National Health and Medical Research Council (ID191222, Melbourne, Australia), a VicHealth Public Health Research Fellowship (2002–2006), and National Health and Medical Research Council Career Development Award (ID491205, 2008–2011) awarded to Stephanie J Brown.
PY - 2010/2
Y1 - 2010/2
N2 - Introduction: Few studies have examined associations of prepregnancy urinary incontinence (UI). Methods: Multicentre prospective pregnancy cohort study (n=1,507) using standardised measures to assess frequency and severity of UI. Results: Prevalence of UI increased from 10.8% in the 12 months before the index pregnancy to 55.9% in the third trimester. Stress incontinence (36.9%) and mixed incontinence (13.1%) were more common during pregnancy than urge incontinence alone (5.9%). UI before pregnancy was associated with childhood enuresis (adjusted odds ratio (AdjOR)=2.4, 95% confidence interval (CI) 1.6-3.4), higher maternal body mass index (AdjOR=2.3, 95% CI 1.4-3.8), and previous miscarriages or terminations (AdjOR=1.6, 95% CI 1.1-2.3). The strongest predictor of incident UI in pregnancy was occasional leakage (less than once a month) before pregnancy (AdjOR=3.6, 95% CI 2.8-4.7). Conclusions: Further research is needed to elucidate the complex interplay of prepregnancy and pregnancy-related factors in the aetiology of UI in nulliparous women.
AB - Introduction: Few studies have examined associations of prepregnancy urinary incontinence (UI). Methods: Multicentre prospective pregnancy cohort study (n=1,507) using standardised measures to assess frequency and severity of UI. Results: Prevalence of UI increased from 10.8% in the 12 months before the index pregnancy to 55.9% in the third trimester. Stress incontinence (36.9%) and mixed incontinence (13.1%) were more common during pregnancy than urge incontinence alone (5.9%). UI before pregnancy was associated with childhood enuresis (adjusted odds ratio (AdjOR)=2.4, 95% confidence interval (CI) 1.6-3.4), higher maternal body mass index (AdjOR=2.3, 95% CI 1.4-3.8), and previous miscarriages or terminations (AdjOR=1.6, 95% CI 1.1-2.3). The strongest predictor of incident UI in pregnancy was occasional leakage (less than once a month) before pregnancy (AdjOR=3.6, 95% CI 2.8-4.7). Conclusions: Further research is needed to elucidate the complex interplay of prepregnancy and pregnancy-related factors in the aetiology of UI in nulliparous women.
KW - Childhood enuresis
KW - Nulliparous
KW - Pregnancy
KW - Prospective cohort study
KW - Urinary incontinence
UR - https://www.scopus.com/pages/publications/76649107679
U2 - 10.1007/s00192-009-1011-x
DO - 10.1007/s00192-009-1011-x
M3 - Article
C2 - 19834637
AN - SCOPUS:76649107679
SN - 0937-3462
VL - 21
SP - 193
EP - 202
JO - International Urogynecology Journal
JF - International Urogynecology Journal
IS - 2
ER -