Wrapping BCR-ABL: It's in the bag

Junia V. Melo; Duncan R. Hewett

doi:10.1182/blood-2010-08-300608

Wrapping BCR-ABL: It's in the bag

Junia V. Melo, Duncan R. Hewett

Research output: Contribution to journal › Comment/debate › peer-review

2 Citations (Scopus)

Abstract

Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).

Original language	English
Pages (from-to)	3382-3383
Number of pages	2
Journal	Blood
Volume	116
Issue number	18
DOIs	https://doi.org/10.1182/blood-2010-08-300608
Publication status	Published or Issued - 4 Nov 2010
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

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10.1182/blood-2010-08-300608

Cite this

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title = "Wrapping BCR-ABL: It's in the bag",

abstract = "Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).",

author = "Melo, {Junia V.} and Hewett, {Duncan R.}",

year = "2010",

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doi = "10.1182/blood-2010-08-300608",

language = "English",

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journal = "Blood",

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T2 - It's in the bag

AU - Melo, Junia V.

AU - Hewett, Duncan R.

PY - 2010/11/4

Y1 - 2010/11/4

N2 - Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).

AB - Leukemia, with its origin in a specific genetic abnormality, will only arise if the cell properly folds and processes the oncogenic protein encoded by the mutant gene. In this issue of Blood, Tsukahara and Maru describe a set of proteins that control the processing of the nascent BCR-ABL oncoprotein, providing new avenues for potential therapeutic intervention in chronic myelogenous leukemia (CML).

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U2 - 10.1182/blood-2010-08-300608

DO - 10.1182/blood-2010-08-300608

M3 - Comment/debate

C2 - 21051563

AN - SCOPUS:78149322317

SN - 0006-4971

VL - 116

SP - 3382

EP - 3383

JO - Blood

JF - Blood

IS - 18

ER -

Wrapping BCR-ABL: It's in the bag

Abstract

ASJC Scopus subject areas

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